DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(dx) and Hectd2

DIOPT Version :9

Sequence 1:NP_001259898.1 Gene:Su(dx) / 33379 FlyBaseID:FBgn0003557 Length:949 Species:Drosophila melanogaster
Sequence 2:NP_001156943.1 Gene:Hectd2 / 226098 MGIID:2442663 Length:775 Species:Mus musculus


Alignment Length:370 Identity:121/370 - (32%)
Similarity:191/370 - (51%) Gaps:30/370 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   594 IKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLF 658
            :.:.|.|..|..||..::.|..| :|:::|.:.|.||.|||.||:::|||.||..::.:|.|.:|
Mouse   416 LNMKVRRTHLVSDSLDELTRKRA-DLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMF 479

  Fly   659 EYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNK------- 716
            .| :|:::   .:..|....|:...|:.:|..:.:|:|:...:...|....||::|:.       
Mouse   480 TY-HKDSH---CHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPVVPSDQ 540

  Fly   717 -------KLTIKDIETIDPEFYNSL--IWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEK 772
                   .:||.|:..:.||..:.|  :...:.|::| .....|.|..|..|.|..:.||..|:|
Mouse   541 STPVGICSVTIDDLCQVMPELAHGLKELLSYEGNVEE-DFYSTFQVFQEEFGVIKSYNLKPGGDK 604

  Fly   773 ERVTEENKEEYITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVE 837
            ..||.:|:.||:.|.|::.:.:.|.:|...|..||:.|.....|......|:|:::||..::|:.
Mouse   605 IPVTNQNRREYVQLYTDFLLNKSIYKQFAAFYCGFHSVCASNALMLLRPEEVEILVCGSPELDMH 669

  Fly   838 DWQRNTIYRHYNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCI 902
            ..||:|.|..|.:....:.:||..|.....|.:.:||.|.||:.||||||.|:|       .|.|
Mouse   670 ALQRSTQYDGYAKTDLTIRYFWDVVLGFPLELQKKLLHFTTGSDRVPVGGMADL-------NFKI 727

  Fly   903 EKVGKET-WLPRSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGF 946
            .|....| |||.:|||||:|.||||||...|.:||...|..:|||
Mouse   728 SKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGF 772

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(dx)NP_001259898.1 C2_E3_ubiquitin_ligase 48..173 CDD:175988
WW 364..396 CDD:197736
WW 397..426 CDD:278809
WW 478..509 CDD:197736
WW 522..554 CDD:197736
HECTc 594..946 CDD:238033 119/368 (32%)
HECTc 620..946 CDD:214523 111/342 (32%)
Hectd2NP_001156943.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..51
HECTc 416..773 CDD:238033 121/370 (33%)
HECTc 439..772 CDD:214523 112/344 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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