Protein Alignment Su(dx) and Yap1

DIOPT Version :9

• Sequence 1: NP_001259898.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_006509915.1
• Gene: Yap1 / 22601
• MGIID: 103262
• Length: 494
• Species: Mus musculus
• Alignment Length: 572
• Identity: 123/572 - (21%)
• Similarity: 189/572 - (33%)
• Gaps: 198/572 - (34%)

  Fly   255 APPVWEQQQQQSQNQQQPLR-----MVNGSGAAVPQTAP-----YPQ---QPPAP----ALARPL 302
            |||...|......:.:..|.     ::|...|.||||.|     .|.   :||.|    ..|...
Mouse    32 APPAGHQVVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTD 96

  Fly   303 TQVYGAL-PE----NTQPAAVYLPAGGGAAVGPPGVAGPPIEQPGVGLPVSQSTDPQLQTQPADD 362
            ....||| |:    ::.||::.|.|.....:...||...|...|..
Mouse    97 AGTAGALTPQHVRAHSSPASLQLGAVSPGTLTASGVVSGPAAAPAA------------------- 142

  Fly   363 EPLPAGWEIRLDQYGRRYYVDHNTRSTYWEKP--TPLPPGWEIRKDGRGRVYYVDHNTRKTTWQR 425
                                 .:.|.:.:|.|  .|||.|||:.|...|:.|:::||.:.||||.
Mouse   143 ---------------------QHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHNDQTTTWQD 186

  Fly   426 PNSERLMHFQHWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQD-DEDALGPLPDGWEKKIQS 489
            |              |..::||.|          .|...:..|.|. ...|.||||||||:.:..
Mouse   187 P--------------RKAMLSQLN----------VPAPASPAVPQTLMNSASGPLPDGWEQAMTQ 227

  Fly   490 DNRVYFVNHKNRTTQWEDPRTQGQEVSLINE-----GPL--PPGWEIRYTAAG------------ 535
            |..||::||||:||.|.|||...:....:|:     .|:  ||....:....|
Mouse   228 DGEVYYINHKNKTTSWLDPRLDPRFGKAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGSSNQQQQ 292

  Fly   536 ----------ERFFVDHNTRRTTFEDPRPGAPKGAK-GVYGVPRAYERSFRWKLSQFRYLCQSNA 589
                      ||..:   .::..|...||.|.:... .....|:..|.:.|   ||...|.|...
Mouse   293 IQLQQLQMEKERLRL---KQQELFRQVRPQAIRNINPSTANAPKCQELALR---SQLPTLEQDGG 351

  Fly   590 LPSHIK---ITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVL 651
            .|:.:.   ::...:|:..:|....:....|..|         :|..|.|
Mouse   352 TPNAVSSPGMSQELRTMTTNSSDPFLNSGTYHSR---------DESTDSG--------------- 392

  Fly   652 NPMYCLFEYANKNNYSLQINPASYVN-----------------------PDHLQYFKFIGRFIAM 693
                     .:.::||:...|..::|                       ||:|:...  |..:.:
Mouse   393 ---------LSMSSYSIPRTPDDFLNSVDEMDTGDTISQSTLPSQQSRFPDYLEALP--GTNVDL 446

  Fly   694 ALYHG--RFIYSGFTMPFYKRMLNKKLTIKDIETI------DPEFYNSLIWV 737
            ....|  ..|.....||..:..|:.:  |.|:|::      |.|.:  |.|:
Mouse   447 GTLEGDAMNIEGEELMPSLQEALSSE--ILDVESVLAATKLDKESF--LTWL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_001259898.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988
		WW	364..396	CDD:197736	3/33 (9%)
		WW	397..426	CDD:278809	14/28 (50%)
		WW	478..509	CDD:197736	18/30 (60%)
		WW	522..554	CDD:197736	7/55 (13%)
		HECTc	594..946	CDD:238033	27/178 (15%)
		HECTc	620..946	CDD:214523	24/149 (16%)
Yap1	XP_006509915.1	FAM181	<61..>141	CDD:373671	22/79 (28%)
		WW	159..188	CDD:238122	14/42 (33%)
		WW	217..246	CDD:366073	16/28 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810