DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(dx) and Hace1

DIOPT Version :9

Sequence 1:NP_001259898.1 Gene:Su(dx) / 33379 FlyBaseID:FBgn0003557 Length:949 Species:Drosophila melanogaster
Sequence 2:XP_006512697.1 Gene:Hace1 / 209462 MGIID:2446110 Length:921 Species:Mus musculus


Alignment Length:347 Identity:149/347 - (42%)
Similarity:210/347 - (60%) Gaps:4/347 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly   596 ITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEY 660
            :.|.|.::|..|...:.:....:|::.:.:.|.||||:.. ||.||||.:||:|::||.|.||. 
Mouse   567 LLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQ-GVVREWFDILSNEIVNPDYALFT- 629

  Fly   661 ANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIET 725
            .:.:..:.|.|..||||||||.||:|.|:.:.:||.|.:.:...||..|||.:|...:..:|:.:
Mouse   630 QSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVAS 694

  Fly   726 IDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEW 790
            ||||:..:|.|:.||:|.:.||||.|||:.:|.|.:....||..|....||:.||.||:.|:||.
Mouse   695 IDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTEL 759

  Fly   791 RMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRH-YNRNSKQ 854
            ||||.|:.|...||:||:..:|...::.|||.||||:|.||.::||.||.:||.|.. |.|....
Mouse   760 RMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPV 824

  Fly   855 VVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVG-KETWLPRSHTCF 918
            :.|||:.|.:...|:|..|||||||:.|||.||||.:||.:|.|.|.|..|. ....||.|.||.
Mouse   825 IQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCI 889

  Fly   919 NRLDLPPYKSYDQLVEKLTFAI 940
            |.|.||.|.|.:.|.::|..|:
Mouse   890 NMLKLPEYPSKEILKDRLLVAL 911

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(dx)NP_001259898.1 C2_E3_ubiquitin_ligase 48..173 CDD:175988
WW 364..396 CDD:197736
WW 397..426 CDD:278809
WW 478..509 CDD:197736
WW 522..554 CDD:197736
HECTc 594..946 CDD:238033 149/347 (43%)
HECTc 620..946 CDD:214523 144/323 (45%)
Hace1XP_006512697.1 ANK repeat 66..95 CDD:293786
Ank_2 69..194 CDD:372319
ANK repeat 97..128 CDD:293786
ANK repeat 130..161 CDD:293786
ANK repeat 163..194 CDD:293786
Ank_2 168..263 CDD:372319
ANK repeat 196..233 CDD:293786
HECTc 566..915 CDD:238033 149/347 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000080
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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