Protein Alignment Su(dx) and Gas7

DIOPT Version :10

• Sequence 1: NP_476753.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: NP_001389747.1
• Gene: Gas7 / 14457
• MGIID: 1202388
• Length: 476
• Species: Mus musculus
• Alignment Length: 534
• Identity: 99/534 - (18%)
• Similarity: 176/534 - (32%)
• Gaps: 192/534 - (35%)

  Fly   479 LPDG--WEKKIQSDNRVYFVNHKNRTTQWED--PRTQGQEVSLINEGPLPPGWEIRYTAAGERFF 539
            :|||  ||.:.....|.:|.....:..:...  |...|:|...:   .|||||....:..|.|::
Mouse    34 VPDGGWWEGEKDDGLRGWFPASYVQLLEKPGMVPPPPGEESQTV---ILPPGWHSYLSPQGRRYY 95

  Fly   540 VDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLF 604
            |:..|..||:|     .|..:.|:...|..:..|....::.:    .::..|:|...|.
Mouse    96 VNTTTNETTWE-----RPSSSPGISASPGPHRSSLPTTVNGY----HASGTPAHPPETA------ 145

  Fly   605 EDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQ 669
                |..:|....:           .:.|......|:                   .:|.| ::.
Mouse   146 ----HMSLRKSTGD-----------SQNLGSSSPGRK-------------------QSKEN-TIT 175

  Fly   670 INPASYVNPD--------------HLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLT- 719
            ||..::.:||              :..||     :.......|....:||.:...|::..|::.
Mouse   176 INCVTFPHPDTMPEQQLLKPTEWSYCDYF-----WADKKDPQGNGTVAGFELLLQKQLKGKQMQK 235

  Fly   720 -----IKDIETIDPEF--------YNSL----------IW--VKDNNIDECGLELWFSVDFEVLG 759
                 |::...|:.|:        .|||          .|  ||.:..||..:.|.||..
Mouse   236 EMSEFIRERIKIEEEYAKNLAKLSQNSLAAQEEGSLGEAWAQVKKSLADEAEVHLKFSAK----- 295

  Fly   760 QIIHHEL-------KENGEKERVTEENKEEYITLMTEWRMTR--GIEQQTKTFLEGFNEVVPLEW 815
              :|.|:       :||.:|:.   :..:.:|..:.:...:|  .:|:..|...|...:   ||
Mouse   296 --LHSEVEKPLMNFRENFKKDM---KKCDHHIADLRKQLASRYASVEKARKALTERQKD---LE- 351

  Fly   816 LKYFDERELELILCGMQDVDVEDWQRNT------------IYRHYNRNSKQVVWFWQFVRETDNE 868
               ...::||:.|....:.|::..:|.:            :|     |..|..||.:.|..|
Mouse   352 ---MKTQQLEIKLSNKTEEDIKKARRKSTQAGDDLMRCVDLY-----NQAQSKWFEEMVTTT--- 405

  Fly   869 KRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHTC-----------FNRLD 922
                                .||      :|..:|:|.    :.|.|.|           ||:..
Mouse   406 --------------------LEL------ERLEVERVE----MIRQHLCQYTQLRHETDMFNQST 440

  Fly   923 LPPYKSYDQLVEKL 936
            :.|   .|||:.|:
Mouse   441 VEP---VDQLLRKV 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_476753.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988
		WW	364..396	CDD:197736
		HUL4	<395..946	CDD:227354	99/534 (19%)
Gas7	NP_001389747.1	SH3_GAS7	5..57	CDD:212763	7/22 (32%)
		WW_FCH_linker	109..201	CDD:465206	16/136 (12%)
		F-BAR_GAS7	214..446	CDD:153333	53/289 (18%)