Protein Alignment Su(dx) and LOC1280030

DIOPT Version :10

• Sequence 1: NP_476753.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_061512305.1
• Gene: LOC1280030 / 1280030
• VectorBaseID: AGAMI1_012596
• Length: 999
• Species: Anopheles gambiae
• Alignment Length: 1012
• Identity: 672/1012 - (66%)
• Similarity: 747/1012 - (73%)
• Gaps: 130/1012 - (12%)

  Fly    49 HQLSVTIEEASLRNNGFLKPNPYVELLIDSKSKRKTDLVKNSYLPKWNEEFTVLITPNSTLHFKV 113
            |||.|.||.|:.|:|||||||||||..||.|:.||||::||:..|||||.||.:::|.|.|||:|
Mosquito     7 HQLIVIIEHATFRSNGFLKPNPYVEFSIDGKTSRKTDIIKNTNTPKWNERFTSIVSPGSVLHFRV 71

  Fly   114 LDHSSFRKDAMLGERIINLAHILQHYNGRCEFLELTIDLFV----TSK-SDNRQ-TKSGELVAIL 172
            |||||||||::||::.:.||.||:||||..|.|||.:||.:    :|| |:.|| .|:||||.:|
Mosquito    72 LDHSSFRKDSLLGQQTVELAGILRHYNGVLELLELNMDLLIDGTGSSKTSEPRQPVKAGELVVVL 136

  Fly   173 NGLKLDMSKL----------------QIQPVAGQQNGNPPVQAVNPSVVSDAAAG-------RSC 214
            :|||:||..|                .:..|.||.:|.|          ||.|..       ||.
Mosquito   137 DGLKIDMRHLGAGAGAMRGNETGTGSGMVNVNGQLSGGP----------SDLAPNGVHYHTLRSS 191

  Fly   215 MIYGGVRARMRLRSSSGNSNGGETRSPLPNGGG-----------------DHRRSTQAPPVWEQQ 262
            ::.||:|||||||.:.|.|...:.:....:.||                 .|.:|..:|   ...
Mosquito   192 ILNGGIRARMRLRGTGGGSTSQQLQPASSSTGGMMNHALVPSSSSSSAAVQHHQSQHSP---ASH 253

  Fly   263 QQQSQNQQQPL--------------------RMVNG-----------------SGAAVPQTA--- 287
            ..||.|.....                    .|.||                 |||:....|
Mosquito   254 ASQSNNNATSTASDCVSSSLNEFSIAGGSYGTMGNGIMTAGSSPNGGGGGGSSSGASSSTGAIRR 318

  Fly   288 ---PYPQQPPAPALARP-----LTQVY---------GALPENTQPAAVYLPAGGGAAVGPPGVAG 335
               .:.||..:|..:..     |..||         ..:|.........||..||:..|.....|
Mosquito   319 SGINWDQQNVSPVASSTGYHARLGPVYSNSSQEGLINGVPGGGHTNTAMLPVAGGSPGGANNGGG 383

  Fly   336 PPIEQPGVGLPVSQSTDPQL--------QTQPADDEPLPAGWEIRLDQYGRRYYVDHNTRSTYWE 392
            ..|..|..|    ..||.||        |..|.||||||||||:|:|::||||||||||||||||
Mosquito   384 ADIPMPMGG----SLTDQQLILQHQQQQQQNPIDDEPLPAGWEMRVDKFGRRYYVDHNTRSTYWE 444

  Fly   393 KPTPLPPGWEIRKDGRGRVYYVDHNTRKTTWQRPNSERLMHFQHWQGQRAHVVSQGNQRYLYSQQ 457
            ||.|||.|||.|:|.||||||||||||.|||||||||||||||||||||.|::||||||:||.|.
Mosquito   445 KPQPLPAGWEQRRDPRGRVYYVDHNTRTTTWQRPNSERLMHFQHWQGQRQHIISQGNQRFLYPQH 509

  Fly   458 QQQPTAVTAQVTQDDEDALGPLPDGWEKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSLINEGP 522
            .||..:::  |..:::|.||||||||||::|.|||||||||||||||||||||||||||::.|||
Mosquito   510 AQQSNSIS--VAHEEDDGLGPLPDGWEKRVQPDNRVYFVNHKNRTTQWEDPRTQGQEVSMLAEGP 572

  Fly   523 LPPGWEIRYTAAGERFFVDHNTRRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQS 587
            |||||||||||.|||||||||.|:|||||||||||||||||||||:|||||||||||||||||||
Mosquito   573 LPPGWEIRYTANGERFFVDHNNRKTTFEDPRPGAPKGAKGVYGVPKAYERSFRWKLSQFRYLCQS 637

  Fly   588 NALPSHIKITVTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLN 652
            |||.||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   638 NALASHIKITLTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLN 702

  Fly   653 PMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKK 717
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   703 PMYCLFEYANKNNYSLQINPASYVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKK 767

  Fly   718 LTIKDIETIDPEFYNSLIWVKDNNIDECGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEE 782
            ||.|||||||||||||||||:|||||||||||||||||||||||||||||:||:|||||||||||
Mosquito   768 LTTKDIETIDPEFYNSLIWVRDNNIDECGLELWFSVDFEVLGQIIHHELKDNGDKERVTEENKEE 832

  Fly   783 YITLMTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRH 847
            ||:||||||||||||:||||||:|||||||||||||||||||||:|||||::||:|||||:||||
Mosquito   833 YISLMTEWRMTRGIEEQTKTFLDGFNEVVPLEWLKYFDERELELMLCGMQEIDVDDWQRNSIYRH 897

  Fly   848 YNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLP 912
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
Mosquito   898 YNRNSKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKDTWLP 962

  Fly   913 RSHTCFNRLDLPPYKSYDQLVEKLTFAIEETEGFCQE 949
            ||||||||||||||||||||||||.:||||||||.||
Mosquito   963 RSHTCFNRLDLPPYKSYDQLVEKLNYAIEETEGFGQE 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_476753.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988	76/129 (59%)
		WW	364..396	CDD:197736	27/31 (87%)
		HUL4	<395..946	CDD:227354	497/550 (90%)
LOC1280030	XP_061512305.1	None