DRSC/TRiP Functional Genomics Resources

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Protein Alignment Su(dx) and herc5.4

DIOPT Version :9

Sequence 1:NP_001259898.1 Gene:Su(dx) / 33379 FlyBaseID:FBgn0003557 Length:949 Species:Drosophila melanogaster
Sequence 2:XP_005160166.1 Gene:herc5.4 / 100148091 ZFINID:ZDB-GENE-090311-7 Length:995 Species:Danio rerio


Alignment Length:355 Identity:98/355 - (27%)
Similarity:172/355 - (48%) Gaps:28/355 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   598 VTRQTLFEDSYHQIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYAN 662
            :.|:::..|:. |.:|...:.....|.:.|.||:|:|..|:|.|:|.|:|...:       |:..
Zfish   660 INRESVLTDTL-QYLRQNTHSFMHPLQVAFIGEDGIDMRGLSAEFFSLISKSFI-------EWDK 716

  Fly   663 KNNYSLQINPASYV--NPDHL---QYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKD 722
            |   .|:::.:|.|  ||.|.   :.|.::|....||||:...|...|.:..:|::|.:|.::.|
Zfish   717 K---ILEVHESSLVWFNPHHTRGNKNFYYLGVICGMALYNRHHINIDFPLALFKKLLQQKPSLDD 778

  Fly   723 IETIDPEFYNSLIWVKDNNIDE-CGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITL 786
            :|.:.|....||..:.:.:.:| ..|:   .:||...||    ||..||.:.:|.:.|:::|:.|
Zfish   779 LEELSPVEARSLKNLLEEDEEEVVNLQ---HLDFTCKGQ----ELVPNGSQIQVNKVNRQKYVDL 836

  Fly   787 MTEWRMTRGIEQQTKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYRHYNRN 851
            ..:....:.::.|.:.|..||::..||:....|...||:.:|.|....:.::.|::..|...:.:
Zfish   837 YVDLEFNKSVKTQFEQFTRGFSKGCPLDAWTMFHPEELQELLHGSPQYNWKELQQSASYEGCSAS 901

  Fly   852 SKQVVWFWQFVRETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKVGKETWLPRSHT 916
            .:.:..||....|...|.:.:.|.|:.||.|||.||.:: ......|..|.:   .:..||.:.|
Zfish   902 DELIKNFWTVFFELSEENKKKFLMFLYGTERVPAGGLSK-RALKISQTDCPD---PDDHLPEAQT 962

  Fly   917 CFNRLDLPPYKSYDQLVEKLTFAIEETEGF 946
            ||.||.||.|...:.|.:||..||.....|
Zfish   963 CFERLVLPKYSDINTLHDKLIHAINSCAVF 992

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Su(dx)NP_001259898.1 C2_E3_ubiquitin_ligase 48..173 CDD:175988
WW 364..396 CDD:197736
WW 397..426 CDD:278809
WW 478..509 CDD:197736
WW 522..554 CDD:197736
HECTc 594..946 CDD:238033 97/353 (27%)
HECTc 620..946 CDD:214523 93/331 (28%)
herc5.4XP_005160166.1 RCC1_2 117..146 CDD:290274
RCC1 133..183 CDD:278826
RCC1 186..235 CDD:278826
RCC1 239..286 CDD:278826
RCC1 294..343 CDD:278826
HECTc 658..993 CDD:294058 98/355 (28%)
HECTc 682..992 CDD:214523 93/330 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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