Protein Alignment Su(dx) and herc4

DIOPT Version :10

• Sequence 1: NP_476753.1
• Gene: Su(dx) / 33379
• FlyBaseID: FBgn0003557
• Length: 949
• Species: Drosophila melanogaster
• Sequence 2: XP_031760534.1
• Gene: herc4 / 100036667
• XenbaseID: XB-GENE-962981
• Length: 1057
• Species: Xenopus tropicalis
• Alignment Length: 669
• Identity: 148/669 - (22%)
• Similarity: 264/669 - (39%)
• Gaps: 151/669 - (22%)

  Fly   340 QPGVGLPVSQSTD----PQLQTQPADDEPLPAGWEIRLDQYGRRYYV--------DHN------- 385
            ||.:...|:.|.:    |:|.:.|.|.|.|            |.|.:        |.|
 Frog   475 QPQIAQQVAASLEKNLIPRLTSSPPDIECL------------RLYLILPECPPMADANNLTSLAI 527

  Fly   386 ---TRSTYWEK-PTPLPPGW------------------------EIRKDG----RGRVYYVDHNT 418
               |.....|| |..:...|                        ::.|:|    ..|::|...||
 Frog   528 PFGTAIVNLEKAPLKVLENWWSLLEPPLFLKVVQLYKDVVVHLLKLSKNGIPLTERRLFYRFLNT 592

  Fly   419 RKTTWQRPNSERLMHFQHWQGQRAHVVSQGNQRYLYSQQQQQPTAVTAQVTQDDEDALGPLPDGW 483
                     :.|::...|...::|..:...::.|::..|.
 Frog   593 ---------ALRVLEILHRVNEKAAQIIPYDKFYIHEVQD------------------------- 623

  Fly   484 EKKIQSDNRVYFVNHKNRTTQWEDPRTQGQEVSLINEGPL----PPGWEIRYTAAGERFFVDHNT 544
                       ||:.:|....|...:..|.:|   |.|..    ||     .|.....|..|...
 Frog   624 -----------FVDIQNDYINWIKQQASGMDV---NHGLYEVADPP-----VTICTYPFVFDAQA 669

  Fly   545 RRTTFEDPRPGAPKGAKGVYGVPRAYERSFRWKLSQFRYLCQSNALPSHIKITVTRQTLFEDSYH 609
            :.|..:         ...|..:..|.:.:.|.....:.:....:..|..| :.|.|..:..|:..
 Frog   670 KTTLLQ---------TDAVIQMQMAVDNAHRQNNLSWLFPATESVDPCLI-LVVRRDNIVGDAME 724

  Fly   610 QIMRLPAYELRRRLYIIFRGEEGLDYGGVSREWFFLLSHEVLNPMYCLFEYANKNNYSLQINPAS 674
            .:.:....:.::.:.:||.|||.:|.|||.:|:|.|:..|:|:|.|.:|.|..::.. :..:..:
 Frog   725 VLRKTKNIDYKKPMRVIFFGEEAIDAGGVRKEFFLLIMRELLDPKYGMFRYYEESRL-IWFSDKT 788

  Fly   675 YVNPDHLQYFKFIGRFIAMALYHGRFIYSGFTMPFYKRMLNKKLTIKDIETIDPEFYNS---LIW 736
            :.:.|   .|..||....:|:|:...|...|.:..||::|.||.:::|::.:.|....|   |:.
 Frog   789 FEDSD---LFHLIGVVCGLAIYNFTIIELHFPLALYKKLLKKKPSLEDLKELMPIIGRSMQQLLD 850

  Fly   737 VKDNNIDE--CGLELWFSVDFEVLGQIIHHELKENGEKERVTEENKEEYITLMTEWRMTRGIEQQ 799
            ..:::|:|  |   |.|::..|..|.....||..||.:..|..:|:::::....::...:.:...
 Frog   851 YTEDDIEETFC---LNFTITVENFGTTEVRELIPNGAEIPVNRKNRQDFVDAYVDYIFNQSVASL 912

  Fly   800 TKTFLEGFNEVVPLEWLKYFDERELELILCGMQDVDVEDWQRNTIYR-HYNRNSKQVVWFWQFVR 863
            ...|..||::|...:.|:.|...||:.::.|....|.::.:::|.|: .|..:...:..||:...
 Frog   913 FSAFSAGFHKVCGSKVLELFQPNELQAMVIGNTAYDWKELEKSTEYKGEYWADHPTIKMFWEIFH 977

  Fly   864 ETDNEKRARLLQFVTGTCRVPVGGFAELMGSNGPQRFCIEKV-GKETWLPRSHTCFNRLDLPPYK 927
            ....||:.:.|.|:||:.|:|:.|...|       :..|:.. |.|.:||.:|||||.||||.|.
 Frog   978 ALPLEKKKQFLLFLTGSDRIPILGMKSL-------KLVIQPTGGGEQFLPVAHTCFNLLDLPKYS 1035

  Fly   928 SYDQLVEKLTFAIEETEGF 946
            ..:.|..||..||:..|||
 Frog  1036 KKETLRSKLIQAIDHYEGF 1054

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(dx)	NP_476753.1	C2_E3_ubiquitin_ligase	48..173	CDD:175988
		WW	364..396	CDD:197736	9/50 (18%)
		HUL4	<395..946	CDD:227354	128/589 (22%)
herc4	XP_031760534.1	ATS1	3..338	CDD:444065
		HECTc	709..1055	CDD:238033	100/361 (28%)