Protein Alignment CG4238 and UPL2

DIOPT Version :9

• Sequence 1: NP_001259896.1
• Gene: CG4238 / 33377
• FlyBaseID: FBgn0031384
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: NP_177189.1
• Gene: UPL2 / 843368
• AraportID: AT1G70320
• Length: 3658
• Species: Arabidopsis thaliana
• Alignment Length: 1148
• Identity: 292/1148 - (25%)
• Similarity: 437/1148 - (38%)
• Gaps: 379/1148 - (33%)

  Fly    84 DPERLPELPP------LDEQRLQR------------------AAL--HLQQKLIL---------- 112
            |||.|..|||      |.:||.||                  |.|  .|:::::|
plant  2632 DPEFLAALPPEIQREVLAQQRAQRMLQQSQGQPVDMDNASIIATLPADLREEVLLTSSEAVLAAL 2696

  Fly   113 -------REWLKDHRLQHHYQRLLAVEVASLEDVYWLEDSRASKILGKDWQL----------WSG 160
                   .:.|:|..::|:..|                    |::.|...:|          .:|
plant  2697 PPPLLAEAQMLRDRAMRHYQAR--------------------SRVFGSSHRLNNRRNGLGYRLTG 2741

  Fly   161 ARQNLPTSKAQ------LDALKAQLWSTVVKSSQHQDAWTWGGMLVVSVSVAGLVTLAAMTQP-- 217
            ..:.:..:..|      .|.||       ||..:       |..||.:.::..|:.|..:.||
plant  2742 MERGVGVTIGQRDVSSSADGLK-------VKEIE-------GDPLVNADALKSLIRLLRLAQPLG 2792

  Fly   218 ---------SLAPEA--RHSLLQYVTGKY-----LLPANCKVQWDWKDPASVGGTMCFVV--RFF 264
                     :|...:  |.:|:|.:....     .||:...:    .:|..:.|....||  |..
plant  2793 KGLLQRLLLNLCAHSFTRANLVQLLLDMIRPEMETLPSELAL----TNPQRLYGCQLNVVYGRSQ 2853

  Fly   265 QRNGQPYPICDTDHFFVEVTEGTRKVVT----------------ISELGS---------STDPNN 304
            ..||.| |:     .|..|.|....:.|                :|:|.|         .||..:
plant  2854 LLNGLP-PL-----VFRRVLEVLTYLATNHSAVADMLFYFDSSLLSQLSSRKGKEKVTHETDSRD 2912

  Fly   305 ANIAKVKF------------TVRTA---GQYKISVLIGASHIAG-SPFLRSFLPGAID------- 346
            ..|..|.|            |...|   |..::.|...||.|.| ||  .|.:|..::
plant  2913 LEIPLVVFLKLLNRPQLLQSTSHLALVMGLLQVVVYTAASRIEGWSP--SSGVPEKLENKPVGEE 2975

  Fly   347 ---------------ARRSRFIRPASTVICCAGAPTLMHIEPRDEFGNSCLFDQNQSDEALQGYQ 396
                           |||..          ||....:....|:.:..|.|:         |.||:
plant  2976 ASSETQKDAESELSVARRKN----------CAELYNIFLQLPQSDLCNLCM---------LLGYE 3021

  Fly   397 ---VAIYDLHGVPVEKL-----QHAIVFAYD-------------KVNSRVSVTALFPEPTCLRAV 440
               ..||.|.|..::||     .|...|..:             :|.:.:|.|....:.||..|.
plant  3022 GLSDKIYSLAGEVLKKLAAVDVTHRKFFTKELSELASGLSSSTVRVLATLSTTQKMSQNTCSMAG 3086

  Fly   441 IS-YRDQQLPNGDFDIIVLSSSDTTLVHKNIASRKHNICYEAKLLS------------------- 485
            .| .|..|         ||||..:|:...|:.:.|.....|..::.
plant  3087 ASILRVLQ---------VLSSLTSTIDDSNVGTDKETDQEEQNIMQGLKVALEPLWQELGQCISM 3142

  Fly   486 -------------------IFGVSKNKPRKVLCYVGPKQNSLIFQVTIKEMILKFIPKRIATFRL 531
                               :.|:|....      :.|...||             :|...|.|.|
plant  3143 TELQLDHTAATSNVNPGDHVLGISPTSS------LSPGTQSL-------------LPLIEAFFVL 3188

  Fly   532 CPSTKFHFLPQLVSQ-------------LHG--PVFIID-----DGAQPKIELASKDRNIIAATF 576
            |...:   .|.::.|             .||  ...|:|     ||:....:...|.|.::
plant  3189 CEKIQ---TPSMLQQDATVTAGEVKESSTHGSSSKTIVDSQKKIDGSVTFSKFVEKHRRLL---- 3246

  Fly   577 THFLLKNIGGSE-------------TFKDKQDFFYHEVRKFHASYYHEKMALKVQREKILESSMK 628
            ..|:.:|....|             .|.:|:.:|...:|..|..:....:.:.|:|..:||.|..
plant  3247 NSFVRQNPSLLEKSFSMMLKAPRLIDFDNKKAYFRSRIRHQHDQHISGPLRISVRRAYVLEDSYN 3311

  Fly   629 AVKGFSVSDWCGNFEVTFQGEQGIDWGGLRREWFELVCSALFDARGGLFCTFHDKHQALVHPNPT 693
            .::..|..|..|...|.||||:|||.|||.|||::|:...:||....||.|.  .:.|...|||.
plant  3312 QLRMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLFTTV--GNDATFQPNPN 3374

  Fly   694 ---RPAHLKLKHFEFAGKMVGKCLFESALGGTYRQLVRARFSRSFLAQLIGLRVHYKYFEQDDPD 755
               :..|  |.:|:|.|:||.|.||:.       ||:...|:|||...::|::|.|...|..|||
plant  3375 SVYQTEH--LSYFKFVGRMVAKALFDG-------QLLDVYFTRSFYKHILGVKVTYHDIEAVDPD 3430

  Fly   756 LYLSKIKYILDTDLDATDTLELYFVEEMYDSSSGQLSKT----IELIPNGAKTRVTNATKNQYLD 816
             |...:|::|:.|:  :|.|:|.|..:..:.......||    .||.|.|...|||..||::|:|
plant  3431 -YYKNLKWLLENDV--SDILDLTFSMDADEEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVD 3492

  Fly   817 ALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLSIFDENELELLMCGTGEYSISDFKAHHIANGNSA 881
            .:|...|.:.::.::::||:|||.:||..|:|||::.|||||:.|..|....|.||       :.
plant  3493 LVADHILTSAIRPQINAFLEGLNELIPRELVSIFNDKELELLISGLPEIDFDDLKA-------NT 3550

  Fly   882 EFRR------VLAWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQEL----NPQ-FQITAAPTF 935
            |:..      |:.|||..|..||:.:|||.|||.||.|::|..||:.|    .|| .||..|  :
plant  3551 EYTSYTVGSPVIRWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKA--Y 3613

  Fly   936 GN---LPTAHTCFNQLCLPDYESYEQFEKSLLLAISEGSEGFG 975
            |:   ||:||||||||.||:|:|.||.::.|||||.|.:||||
plant  3614 GSPERLPSAHTCFNQLDLPEYQSKEQVQERLLLAIHEANEGFG 3656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720	31/140 (22%)
		Filamin	238..336	CDD:279024	31/140 (22%)
		HECTc	615..975	CDD:238033	150/380 (39%)
		HECTc	642..974	CDD:214523	141/352 (40%)
UPL2	NP_177189.1	DUF908	88..358	CDD:283630
		DUF913	416..765	CDD:283642
		UBA_atUPL1_2_like	1275..1312	CDD:270512
		DUF4414	2593..2688	CDD:291075	16/55 (29%)
		HECTc	3296..3656	CDD:238033	150/382 (39%)
		HECTc	3320..3655	CDD:214523	143/357 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11254
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	5	4.870