DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4238 and UPL5

DIOPT Version :9

Sequence 1:	NP_001259896.1	Gene:	CG4238 / 33377	FlyBaseID:	FBgn0031384	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_192994.1	Gene:	UPL5 / 826870	AraportID:	AT4G12570	Length:	873	Species:	Arabidopsis thaliana

Alignment Length:	409	Identity:	119/409 - (29%)
Similarity:	179/409 - (43%)	Gaps:	47/409 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   596 FFYHEVRKFHA-------------SYYHEKMALKVQREKILESSMKAVKGFSVSDWCGNFEVTFQ 647
            |.|.|...|.|             ..:.|...:.:.|..:|..|.:.:.|.|.....|...:.|:
plant   481 FEYKEATNFEARRHLAMLLFPDVKEDFEEMHEMLIDRSNLLSESFEYIVGASPEALHGGLFMEFK 545

  Fly   648 GEQGIDWGGLRREWFELVCSALFDARGGLFCTFHDKHQALVHPNPTR---PAHLKLKHFEFAGKM 709
            .|:... .|:.||||.|||..:|:.:..||....|..:.. .|||..   |.|...  |||.|::
plant   546 NEEATG-PGVLREWFYLVCQEIFNPKNTLFLRSADDFRRF-SPNPASKVDPLHPDF--FEFTGRV 606

  Fly   710 VGKCLFESALGGTYRQLVRARFSRSFLAQLIGLRVHYKYFEQDDPDLYLSKIKYILDTD---LDA 771
            :       ||...::..|...|.|.|..||.||::..:..:..|..:| :..|.||:.|   .|:
plant   607 I-------ALALMHKVQVGVLFDRVFFLQLAGLKISLEDIKDTDRIMY-NSCKQILEMDPEFFDS 663

  Fly   772 TDTLELYFVEEMYDSSSGQLSK--TIELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKDEVDSF 834
            ...|.|.||.|     :.:|.|  ||||.|:|....|.:..:.||:|.|.::|....:.::|..|
plant   664 NAGLGLTFVLE-----TEELGKRDTIELCPDGKLKAVNSKNRKQYVDLLIERRFATPILEQVKQF 723

  Fly   835 LKGLNSIIPDNL--LSIFDENELE----LLMCGTGEYSISDFKAHHIANGNSAEFRRVLAWFWAG 893
            .:|...::..::  .|.|....||    :|..|....||.|:|||...|| ..|..|.:.|||..
plant   724 SRGFTDMLSHSVPPRSFFKRLYLEDLDGMLRGGENPISIDDWKAHTEYNG-FKETDRQIDWFWKI 787

  Fly   894 VSNFSQTEMARLLQFTTGCSQLPPGGFQELNPQFQI-TAAPTFGNLPTAHTCFNQLCLPDYESYE 957
            :...::.|...:|.|.|....:|..||:.|:.:..| ........||.:||||.:||:|.|.:..
plant   788 LKKMTEEEQRSILFFWTSNKFVPVEGFRGLSSKLYIYRLYEANDRLPLSHTCFYRLCIPRYPTIT 852

  Fly   958 QFEKSL-LLAISEGSEGFG 975
            ..|:.| |:|....|..||
plant   853 LMEQRLRLIAQDHVSSSFG 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720
		Filamin	238..336	CDD:279024
		HECTc	615..975	CDD:238033	111/375 (30%)
		HECTc	642..974	CDD:214523	105/347 (30%)
UPL5	NP_192994.1	UBQ	95..167	CDD:214563
		ubiquitin	102..168	CDD:278661
		HECTc	511..871	CDD:238033	111/377 (29%)
		HECTc	540..860	CDD:214523	102/337 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11254
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910