DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4238 and MAGIX

DIOPT Version :9

Sequence 1:	NP_001259896.1	Gene:	CG4238 / 33377	FlyBaseID:	FBgn0031384	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_079135.3	Gene:	MAGIX / 79917	HGNCID:	30006	Length:	334	Species:	Homo sapiens

Alignment Length:	129	Identity:	26/129 - (20%)
Similarity:	39/129 - (30%)	Gaps:	58/129 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 PEDASLRSDLVLIRSFV----------------------VYKGRPPDHATRFDISMLVSHIN--- 47
            |..||....:.|:|.:.                      :.|..|.....|.::..||.|||
Human   117 PSQASGHFSVELVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGES 181

  Fly    48 VGGVMHA------ATGG-----------KTFPTLKVKLCFGESMGISSLSSCGDPER--LPELP 92
            ..|:.||      ..||           :|.|        |:..|:      |:|.:  :|..|
Human   182 TQGLTHAQAVERIRAGGPQLHLVIRRPLETHP--------GKPRGV------GEPRKGVVPSWP 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720
		Filamin	238..336	CDD:279024
		HECTc	615..975	CDD:238033
		HECTc	642..974	CDD:214523
MAGIX	NP_079135.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		PDZ_signaling	124..206	CDD:238492	15/81 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..306		8/37 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900