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Protein Alignment CG4238 and Smurf1

DIOPT Version :9

Sequence 1:	NP_001259896.1	Gene:	CG4238 / 33377	FlyBaseID:	FBgn0031384	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	XP_006504947.1	Gene:	Smurf1 / 75788	MGIID:	1923038	Length:	757	Species:	Mus musculus

Alignment Length:	454	Identity:	135/454 - (29%)
Similarity:	215/454 - (47%)	Gaps:	61/454 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   536 KFHFLPQLVSQLHGPVFIIDDGAQPKIELAS----KDRNIIAATFTHFLLKNIGGSETFKDKQDF 596
            :.|.:.....||..|       :|| ::|.|    :|..:.|..:...|::          |...
Mouse   338 RLHHIMNHQCQLKEP-------SQP-LQLPSEGSVEDEELPAQRYERDLVQ----------KLKV 384

  Fly   597 FYHEVRKFHASYYHEKMALKVQREKILESSMKAVKGFSVSDWCGNFEVTFQGEQGIDWGGLRREW 661
            ..||:........|  ..::|.||:|.|.|.:.:......|......|.|:||:|:|:||:.|||
Mouse   385 LRHELSLQQPQAGH--CRIEVSREEIFEESYRQIMKMRPKDLKKRLMVKFRGEEGLDYGGVAREW 447

  Fly   662 FELVCSALFDARGGLFCTFHDKHQAL-VHPNPT-RPAHLKLKHFEFAGKMVGKCLFESALGGTYR 724
            ..|:|..:.:...|||....|....| ::|:.: .|.|  |.:|.|.|:::|..:|.    |.|
Mouse   448 LYLLCHEMLNPYYGLFQYSTDNIYTLQINPDSSINPDH--LSYFHFVGRIMGLAVFH----GHY- 505

  Fly   725 QLVRARFSRSFLAQLIGLRVHYKYFEQDDPDLYLSKIKYILDTDLDATDTLELYFVEEMYDSSSG 789
              :...|:..|..||:|..:.....|..||:|:.|.: :||:.|:  |..|:..|..|  .::.|
Mouse   506 --INGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLV-WILENDI--TPVLDHTFCVE--HNAFG 563

  Fly   790 QLSKTIELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLSIFDENE 854
            ::.:. ||.|||....||...|.:|:......|....::.:..:..||.|.:||.:||..||:.|
Mouse   564 RILQH-ELKPNGRNVPVTEENKKEYVRLYVNWRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKE 627

  Fly   855 LELLMCGTGEYSISDFKA-----HHIANGNSAEFRRVLAWFWAGVSNFSQTEMARLLQFTTGCSQ 914
            |||::.|..:..::|:|:     |.:|:.|      ::.|||..|..|.:...||||||.||.::
Mouse   628 LELIIGGLDKIDLNDWKSNTRLKHCVADSN------IVRWFWQAVETFDEERRARLLQFVTGSTR 686

  Fly   915 LPPGGFQELNPQFQITAAPTF---------GNLPTAHTCFNQLCLPDYESYEQFEKSLLLAISE 969
            :|..||:.|...........|         .|||.||||||::.:|.|||||:..:.||.|:.|
Mouse   687 VPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEE 750

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.