DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4238 and Magi2

DIOPT Version :9

Sequence 1:NP_001259896.1 Gene:CG4238 / 33377 FlyBaseID:FBgn0031384 Length:977 Species:Drosophila melanogaster
Sequence 2:XP_006535806.1 Gene:Magi2 / 50791 MGIID:1354953 Length:1414 Species:Mus musculus


Alignment Length:411 Identity:76/411 - (18%)
Similarity:133/411 - (32%) Gaps:146/411 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   676 LFCTFHDKH--QALVHPNPTRPAHLKLK-----HFEFAGKMV------GKCLF---ESALGGTYR 724
            ::.|::..|  :.....||...|..||:     |.|...|.:      .|.||   .|.|.||:.
Mouse   360 IYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGAKPLQAPGFREKPLFTRDASQLKGTFL 424

  Fly   725 QLVRARFSRSFLAQLIGLRVHYKYFEQDDPDLYLSKIKYIL-------DTDLDATDTLELYFVEE 782
            .....:.:..|...:||         .|:||.:| ::|.::       |..::..|.  :.::.|
Mouse   425 STTLKKSNMGFGFTIIG---------GDEPDEFL-QVKSVIPDGPAAQDGKMETGDV--IVYINE 477

  Fly   783 --MYDSSSGQLSKTIELIPNGAKTR---------------------------------VTNATKN 812
              :...:...:.|..:.:|.|....                                 :.|...|
Mouse   478 VCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHN 542

  Fly   813 --QYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLS------IFDEN---------ELELLMC 860
              .||:.::  |...:|.|..|.....|:|:..|..|.      :.|:|         :.||:..
Mouse   543 YETYLEYIS--RTSQSVPDITDRPPHSLHSMPADGQLDGTYPPPVHDDNVSMASSGATQAELMTL 605

  Fly   861 -------GTGEYSISDFKAHH-------------IANGN-SAEFRRVLAWFWAGVSNFSQTEMAR 904
                   |.| ::|:|.....             :..|: ..|..:      ..|.|.|.||:..
Mouse   606 TIVKGAQGFG-FTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQ------QNVQNLSHTEVVD 663

  Fly   905 LLQFTTGCSQ----LPPGGF---------------QELNPQFQITAAPTFGNLPTAHTCFNQLCL 950
            :|:.....|:    :..|||               .:.:||..::|.....|||.. ...::...
Mouse   664 ILKDCPVGSETSLIIHRGGFFSPWKTPKPMMDRWENQGSPQTSLSAPAVPQNLPFP-PALHRSSF 727

  Fly   951 PDY---------ESYEQFEKS 962
            ||.         :.||.:|||
Mouse   728 PDSTEAFDPRKPDPYELYEKS 748

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4238NP_001259896.1 IG_FLMN 238..336 CDD:214720
Filamin 238..336 CDD:279024
HECTc 615..975 CDD:238033 76/411 (18%)
HECTc 642..974 CDD:214523 76/411 (18%)
Magi2XP_006535806.1 PDZ_signaling 22..96 CDD:238492
NK 118..290 CDD:388413
WW 303..332 CDD:366073
WW 349..378 CDD:366073 2/17 (12%)
PDZ 427..508 CDD:214570 14/92 (15%)
PDZ 601..682 CDD:214570 15/87 (17%)
MAGI_u5 681..755 CDD:374709 16/69 (23%)
PDZ 774..860 CDD:214570
PDZ_signaling 919..1006 CDD:238492
PDZ_signaling 1138..1218 CDD:238492
MAGI_u1 1245..1285 CDD:374706
PHA03307 <1255..>1407 CDD:223039
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.