Protein Alignment CG4238 and ube3a

DIOPT Version :9

• Sequence 1: NP_001259896.1
• Gene: CG4238 / 33377
• FlyBaseID: FBgn0031384
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: XP_012812141.1
• Gene: ube3a / 407881
• XenbaseID: XB-GENE-948557
• Length: 908
• Species: Xenopus tropicalis
• Alignment Length: 578
• Identity: 135/578 - (23%)
• Similarity: 256/578 - (44%)
• Gaps: 93/578 - (16%)

  Fly   440 VIS--YRDQQLPNGDFDIIVLSSSDTTLVHKNIASRK----HN---------ICYEAKLLSIFGV 489
            |||  :..:.|.|.|..|:..:.....:.:.|:...:    ||         ...|..|..:.|.
 Frog   384 VISNEFNSRNLVNDDDAIVAATKCLKMVYYSNVVGGEIETDHNEEEDDEPVPESSELTLQELLGE 448

  Fly   490 SKNKPRKVLCYVGPKQNSLIFQVTIKEMILKFIPKRIATFRLCPSTKFHFLPQLVSQLHGPVFII 554
            .:...:      ||:.:.|..::.:|.:..:   |.:..|.           :.|::....|..:
 Frog   449 ERRNKK------GPRVDPLETELGVKSIDCR---KPLIPFE-----------EFVNEPLNDVLEM 493

  Fly   555 D-DGAQPKIELASKDRNIIAATFTHFLLKNIGGSETFKDKQDFFYHEVRKFHASY-------YHE 611
            | |....|:|..:|...:......:.:.||:|   .:.|.:...|.| |:....|       .:.
 Frog   494 DKDYTFFKVETENKFSFMTCPFILNAVTKNLG---LYYDNRIRMYSE-RRITVLYSLVQGQQLNP 554

  Fly   612 KMALKVQREKILESSMKAVKGFSV---SDWCGNFEVTFQGEQGIDWGGLRREWFELVCSALFDAR 673
            .:.|||:|:.|::.::..::..::   :|......|.|:||||:|.||:.:|:|:||...:|:..
 Frog   555 YLRLKVRRDHIIDDALVRLEMIAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPD 619

  Fly   674 GGLFCTFHD--KHQALVHPNPTRPAHLKLK-HFEFAGKMVGKCLFESALGGTYRQLVRARFSRSF 735
            .|:| |:.:  ||...      .|:..:.: .|...|.::|..::.:.:...:..:|..|
 Frog   620 IGMF-TYDESTKHSWF------NPSSFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYR----- 672

  Fly   736 LAQLIGLRVHYKYFEQDDPDLYLSKIKYILDTDLDATDTLELYFVEEMYDSSSGQLSKT------ 794
              :|:|.:..::......|.||.| :|.:|:.:.:..:.:.:.|          |:|:|
 Frog   673 --KLMGKKGTFRDLADSHPVLYQS-LKELLEYEGNVEEDMMMTF----------QISQTDLFGNP 724

  Fly   795 --IELIPNGAKTRVTNATKNQYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLS-IFDENELE 856
              .:|..||.|..:||..:.:::.......|..:|:.:..:|.:|.:.:..::.|. :|...|:|
 Frog   725 LMHDLKENGDKIPITNENRKEFVSLYTDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIE 789

  Fly   857 LLMCGTGEYSISDFKAHHIANGNSAEFRRVLAWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQ 921
            ||:||:........|.....:|.......::..||..|::|::.:....||||||..:.|.||..
 Frog   790 LLICGSRNLDFQALKDTTEYDGGYTRDSNIIKEFWEIVNSFTEEQKRLFLQFTTGTDRAPVGGLG 854

  Fly   922 ELNPQFQITA--APTFGNLPTAHTCFNQLCLPDYESYEQFEKSLLLAISEGSEGFGMV 977
            :|.   .|.|  .|....|||:|||||.|.||:|.:.|:.::.||.||:. ::||||:
 Frog   855 KLK---MIIAKNGPDTDRLPTSHTCFNVLLLPEYSNKEKLKERLLKAITY-AKGFGML 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720
		Filamin	238..336	CDD:279024
		HECTc	615..975	CDD:238033	98/376 (26%)
		HECTc	642..974	CDD:214523	91/345 (26%)
ube3a	XP_012812141.1	AZUL	58..112	CDD:374628
		HECTc	556..906	CDD:238033	98/378 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910