DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4238 and yki

DIOPT Version :9

Sequence 1:	NP_001259896.1	Gene:	CG4238 / 33377	FlyBaseID:	FBgn0031384	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	155	Identity:	28/155 - (18%)
Similarity:	68/155 - (43%)	Gaps:	25/155 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   743 RVHY-----KYFEQDDPDL-YLSKIKYILDTDLDATDTLELYFVEEMYDSSSGQLSKTIELIPNG 801
            :::|     |..:.:||.: |..:.:.::...:...|.|     :....:::..::..:..:|:|
  Fly   279 QIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQNDVL-----QTTKQTTTSTIANNLGPLPDG 338

  Fly   802 AKTRVTNATKNQYLDALAQQRLCNNVKDEVDSFLKGLNSI-IPDNLLSIFDENELELLMCGTGEY 865
            .:..||.:....:::.:.:....|:.:.:     .||:.: .||||:|..   ::|..:|..
  Fly   339 WEQAVTESGDLYFINHIDRTTSWNDPRMQ-----SGLSVLDCPDNLVSSL---QIEDNLCSN--- 392

  Fly   866 SISDFKAHHIANGNSAEFRRVLAWF 890
            ..:|.:|  |.|..|:.....|.|:
  Fly   393 LFNDAQA--IVNPPSSHKPDDLEWY 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720
		Filamin	238..336	CDD:279024
		HECTc	615..975	CDD:238033	28/155 (18%)
		HECTc	642..974	CDD:214523	28/155 (18%)
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	25/142 (18%)
		WW	266..295	CDD:395320	2/15 (13%)
		WW	335..364	CDD:395320	5/28 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900