Protein Alignment CG4238 and Ube3a

DIOPT Version :9

• Sequence 1: NP_001259896.1
• Gene: CG4238 / 33377
• FlyBaseID: FBgn0031384
• Length: 977
• Species: Drosophila melanogaster
• Sequence 2: NP_001178766.1
• Gene: Ube3a / 361585
• RGDID: 1306361
• Length: 868
• Species: Rattus norvegicus
• Alignment Length: 628
• Identity: 148/628 - (23%)
• Similarity: 275/628 - (43%)
• Gaps: 112/628 - (17%)

  Fly   391 ALQGYQVAIYDLHGVP-----VEKLQHAIVFAY--DKVNSRVSVT---ALFPEPTCLRAVISYRD 445
            |.||..:.::..:...     :|..|..|.:..  ::.|||..|.   |:.....||: ::.|.:
  Rat   312 AAQGKLIRLWSKYSADQIRRMMETFQQLITYKVISNEFNSRNLVNDDDAIVAASKCLK-MVYYAN 375

  Fly   446 QQLPNGDFDIIVLSSSDTTLVHKNIASRKHNICYEAKLLSIFGVSKNKPRKVLCYVGPKQNSLIF 510
              :..||.|.......|...:.::         .|..|..:.|..:...:      ||:.:.|..
  Rat   376 --VVGGDVDTNHNEEDDEEPIPES---------SELTLQELLGEERRNKK------GPRVDPLET 423

  Fly   511 QVTIKEMILKFIPKRIATFRLCPSTKFHFLPQLVSQLHGPVFIID-DGAQPKIELASKDRNIIAA 574
            ::.:|.:..:   |.:.:|.           :.:::....|..:| |....|:|..:|...:...
  Rat   424 EIGVKTLDCR---KPLISFE-----------EFINEPLNDVLEMDKDYTFFKVETENKFSFMTCP 474

  Fly   575 TFTHFLLKNIGGSETFKDKQDFFYHEVRKFHASY-------YHEKMALKVQREKILESSMKAVKG 632
            ...:.:.||:|   .:.|.:...|.| |:....|       .:..:.|||:|:.|::.::..::.
  Rat   475 FILNAVTKNLG---LYYDNRIRMYSE-RRITVLYSLVQGQQLNPYLRLKVRRDHIIDDALVRLEM 535

  Fly   633 FSV---SDWCGNFEVTFQGEQGIDWGGLRREWFELVCSALFDARGGLFCTFHDKHQALVHPNPTR 694
            .::   :|......|.|:||||:|.||:.:|:|:||...:|:...|:|.  :|:...|...||:
  Rat   536 IAMENPADLKKQLYVEFEGEQGVDEGGVSKEFFQLVVEEIFNPDIGMFT--YDEATRLFWFNPS- 597

  Fly   695 PAHLKLKHFEFAGK------MVGKCLFESALGGTYRQLVRARFSRSFLAQLIGLRVHYKYFEQDD 753
                   .||..|:      ::|..::.:.:...:..:|..|       :|:|.:..:.......
  Rat   598 -------SFETEGQFTLIGIVLGLAIYNNCILDVHFPMVVYR-------KLMGKKGTFCDLGDSH 648

  Fly   754 PDLYLSKIKYILDTDLDATDTLELYFVEEMYDSSSGQLSKT--------IELIPNGAKTRVTNAT 810
            |.||.| :|.:|:.:.:..|.:.:.|          |:|:|        .:|..||.|..:||..
  Rat   649 PILYQS-LKDLLEYEGNVEDDMMITF----------QISQTDLFGNPMMYDLKENGDKIPITNEN 702

  Fly   811 KNQYLDALAQQRLCNNVKDEVDSFLKGLNSIIPDNLLS-IFDENELELLMCGTGEYSISDFKAHH 874
            :.:::...:...|..:|:.:..:|.:|.:.:..::.|. :|...|:|||:||:...   ||:|..
  Rat   703 RKEFVSLYSDYILNKSVEKQFKAFRRGFHMVTNESPLKYLFRPEEIELLICGSRNL---DFQALE 764

  Fly   875 IANGNSAEFRR---VLAWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQELNPQFQITA--APT 934
            ........:.|   |:..||..|.:|:..:....||||||..:.|.||..:|.   .|.|  .|.
  Rat   765 ETTEYDGGYTRESVVIREFWEIVHSFTDEQKRLFLQFTTGTDRAPVGGLGKLK---MIIAKNGPD 826

  Fly   935 FGNLPTAHTCFNQLCLPDYESYEQFEKSLLLAISEGSEGFGMV 977
            ...|||:|||||.|.||:|.|.|:.::.||.||:. ::||||:
  Rat   827 TERLPTSHTCFNVLLLPEYSSKEKLKERLLKAITY-AKGFGML 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720
		Filamin	238..336	CDD:279024
		HECTc	615..975	CDD:238033	104/382 (27%)
		HECTc	642..974	CDD:214523	97/351 (28%)
Ube3a	NP_001178766.1	AZUL	27..81	CDD:406862
		HECTc	516..866	CDD:238033	104/384 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900