DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG4238 and Trip12

DIOPT Version :9

Sequence 1:NP_001259896.1 Gene:CG4238 / 33377 FlyBaseID:FBgn0031384 Length:977 Species:Drosophila melanogaster
Sequence 2:XP_038939619.1 Gene:Trip12 / 316575 RGDID:1306607 Length:2074 Species:Rattus norvegicus


Alignment Length:431 Identity:111/431 - (25%)
Similarity:165/431 - (38%) Gaps:107/431 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   617 VQREKILESSMKAVKGFSVSDWCGNFEVTFQGEQGIDWGGLRREWFELVCSALFDA-----RG-- 674
            |.||::|:.:...::....|.  ...|:.::.|.|...|. ..|::.||...|..|     ||  
  Rat  1675 VNREELLKQAESVMQDLGSSR--AMLEIQYENEVGTGLGP-TLEFYALVSQELQRADLGLWRGEE 1736

  Fly   675 --------------------GLFCTFHDKHQALVHPNPTRPAHL---KLKHFEFAGKMVGKCLFE 716
                                |||        ||......:|||:   |:| |.|.||::.|.:.:
  Rat  1737 VTLSNPKGSQEGTKYIQNLQGLF--------ALPFGRTAKPAHIAKVKMK-FRFLGKLMAKAIMD 1792

  Fly   717 SALGGT------YRQLVRARFSRSF-----LAQLIGLRVHY--------KYFEQDDPDLYLSKIK 762
            ..|...      |:.::|...|.:.     :..::...|::        |..|||......| ::
  Rat  1793 FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKES-LQ 1856

  Fly   763 YILDT---------DLDATDTLELYFVEEMYDSSSGQLSKTIELIPNGAKTRVTNATKNQYLDAL 818
            |.|:|         ||....||..:              ..|||...|....||.....:||..:
  Rat  1857 YALETLTMNGCSVEDLGLDFTLPGF--------------PNIELKKGGKDIPVTIHNLEEYLRLV 1907

  Fly   819 AQQRLCNNVKDEVDSFLKGLNSIIPDNLLSIFDENELELLMCGTGEYSISDFKA--------HHI 875
            ....|...|..:.|||..|..|:.|.:.|..|...||:.|:||: :....|.|.        |..
  Rat  1908 IFWALNEGVCRQFDSFRDGFESVFPLSHLQYFYPEELDQLLCGS-KADTWDAKTLMECCRPDHGY 1971

  Fly   876 ANGNSAEFRRVLAWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQELNPQFQITAAPTFGN--- 937
            .:.:     |.:.:.:..:|:|...:....|||.||..:||.|||:.|||...| ...||.:   
  Rat  1972 THDS-----RAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTI-VRKTFESTEN 2030

  Fly   938 ----LPTAHTCFNQLCLPDYESYEQFEKSLLLAISEGSEGF 974
                ||:..||.|.|.||||.|.|.....||:|..||.:.|
  Rat  2031 PDDFLPSVMTCVNYLKLPDYSSIEIMRDKLLIAAREGQQSF 2071

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4238NP_001259896.1 IG_FLMN 238..336 CDD:214720
Filamin 238..336 CDD:279024
HECTc 615..975 CDD:238033 111/431 (26%)
HECTc 642..974 CDD:214523 105/404 (26%)
Trip12XP_038939619.1 SRP1 489..>714 CDD:227396
WWE 814..876 CDD:397111
HECTc 1672..2072 CDD:238033 111/431 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.