DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4238 and Bag3

DIOPT Version :9

Sequence 1:	NP_001259896.1	Gene:	CG4238 / 33377	FlyBaseID:	FBgn0031384	Length:	977	Species:	Drosophila melanogaster
Sequence 2:	NP_038891.4	Gene:	Bag3 / 29810	MGIID:	1352493	Length:	577	Species:	Mus musculus

Alignment Length:	88	Identity:	25/88 - (28%)
Similarity:	30/88 - (34%)	Gaps:	25/88 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 SMGISSLSSCGDPERLPELPPLDEQRLQRAA----LHLQQKLILREWLKDHRLQHHYQRLLAVEV 133
            |.|.|||.|...|.....:|.:.||.:.|.|    .|..||.             ||..... |.
Mouse   196 SSGRSSLGSHQLPRGYIPIPVIHEQNITRPAAQPSFHQAQKT-------------HYPAQQG-EY 246

  Fly   134 ASLEDVYWLEDSRASKILGKDWQ 156
            ...:.||       .||.|.||:
Mouse   247 QPQQPVY-------HKIQGDDWE 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4238	NP_001259896.1	IG_FLMN	238..336	CDD:214720
		Filamin	238..336	CDD:279024
		HECTc	615..975	CDD:238033
		HECTc	642..974	CDD:214523
Bag3	NP_038891.4	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..81
		WW	23..55	CDD:197736
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	126..207		6/10 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	229..427		13/55 (24%)
		BAG	426..503	CDD:214591
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	524..577
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900