DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4238 and Trip12

DIOPT Version :9

Sequence 1:NP_001259896.1 Gene:CG4238 / 33377 FlyBaseID:FBgn0031384 Length:977 Species:Drosophila melanogaster
Sequence 2:XP_011236956.1 Gene:Trip12 / 14897 MGIID:1309481 Length:2074 Species:Mus musculus


Alignment Length:431 Identity:110/431 - (25%)
Similarity:164/431 - (38%) Gaps:107/431 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   617 VQREKILESSMKAVKGFSVSDWCGNFEVTFQGEQGIDWGGLRREWFELVCSALFDA-----RG-- 674
            |.||::|:.:...::....|.  ...|:.::.|.|...|. ..|::.||...|..|     ||  
Mouse  1675 VNREELLKQAESVMQDLGSSR--AMLEIQYENEVGTGLGP-TLEFYALVSQELQRADLCLWRGEE 1736

  Fly   675 --------------------GLFCTFHDKHQALVHPNPTRPAHL---KLKHFEFAGKMVGKCLFE 716
                                |||        ||......:|||:   |:| |.|.||::.|.:.:
Mouse  1737 VTLSNPKGSQEGTKYIQNLQGLF--------ALPFGRTAKPAHIAKVKMK-FRFLGKLMAKAIMD 1792

  Fly   717 SALGGT------YRQLVRARFSRSF-----LAQLIGLRVHY--------KYFEQDDPDLYLSKIK 762
            ..|...      |:.::|...|.:.     :..::...|::        |..|||......| ::
Mouse  1793 FRLVDLPLGLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKES-LQ 1856

  Fly   763 YILDT---------DLDATDTLELYFVEEMYDSSSGQLSKTIELIPNGAKTRVTNATKNQYLDAL 818
            |.|:|         ||....||..:              ..|||...|....||.....:||..:
Mouse  1857 YALETLTMNGCSVEDLGLDFTLPGF--------------PNIELKKGGKDIPVTIHNLEEYLRLV 1907

  Fly   819 AQQRLCNNVKDEVDSFLKGLNSIIPDNLLSIFDENELELLMCGTGEYSISDFKA--------HHI 875
            ....|...|..:.|||..|..|:.|...|..|...||:.|:||: :....|.|.        |..
Mouse  1908 IFWALNEGVCRQFDSFRDGFESVFPLCHLQYFYPEELDQLLCGS-KADTWDAKTLMECCRPDHGY 1971

  Fly   876 ANGNSAEFRRVLAWFWAGVSNFSQTEMARLLQFTTGCSQLPPGGFQELNPQFQITAAPTFGN--- 937
            .:.:     |.:.:.:..:|:|...:....|||.||..:||.|||:.|||...| ...||.:   
Mouse  1972 THDS-----RAVKFLFEILSSFDNEQQRLFLQFVTGSPRLPVGGFRSLNPPLTI-VRKTFESTEN 2030

  Fly   938 ----LPTAHTCFNQLCLPDYESYEQFEKSLLLAISEGSEGF 974
                ||:..||.|.|.||||.|.:.....||:|..||.:.|
Mouse  2031 PDDFLPSVMTCVNYLKLPDYSSIDIMRDKLLIAAREGQQSF 2071

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4238NP_001259896.1 IG_FLMN 238..336 CDD:214720
Filamin 238..336 CDD:279024
HECTc 615..975 CDD:238033 110/431 (26%)
HECTc 642..974 CDD:214523 104/404 (26%)
Trip12XP_011236956.1 SRP1 489..>714 CDD:227396
WWE 814..876 CDD:397111
HECTc 1672..2072 CDD:238033 110/431 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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