Protein Alignment Npc2a and Npc2

DIOPT Version :9

• Sequence 1: NP_608637.1
• Gene: Npc2a / 33374
• FlyBaseID: FBgn0031381
• Length: 148
• Species: Drosophila melanogaster
• Sequence 2: NP_075898.1
• Gene: Npc2 / 67963
• MGIID: 1915213
• Length: 149
• Species: Mus musculus
• Alignment Length: 145
• Identity: 55/145 - (37%)
• Similarity: 79/145 - (54%)
• Gaps: 5/145 - (3%)

  Fly     5 AVIACAALVVFAGA--LEFSDCGSKTGKFTRVAIEGCDTTKAECILKRNTTVSFSIDFALAEEAT 67
            |.|...|||..:.|  |.|.|||||.|....|.:..|.|.  .|.|.:..:.|.:|.|....::.
Mouse     6 ATILLLALVAASQAEPLHFKDCGSKVGVIKEVNVSPCPTD--PCQLHKGQSYSVNITFTSGTQSQ 68

  Fly    68 AVKTVVHGKVLGIEMPFPLANPDACVDSGLKCPLEKDESYRYTATLPVLRSYPKVSVLVKWELQD 132
            ....:|||.:.||.:|||:..||.| .||:.||::||:.|.|...|||...||.:.::|:|:|:|
Mouse    69 NSTALVHGILEGIRVPFPIPEPDGC-KSGINCPIQKDKVYSYLNKLPVKNEYPSIKLVVEWKLED 132

  Fly   133 QDGADIICVEIPAKI 147
            ....::.|.|||.:|
Mouse   133 DKKNNLFCWEIPVQI 147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npc2a	NP_608637.1	Npc2_like	21..145	CDD:238458	46/123 (37%)
Npc2	NP_075898.1	Npc2_like	24..145	CDD:238458	46/123 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839274
Domainoid	1	1.000	102	1.000	Domainoid score	I6857
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4697
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4937
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49115
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007859
OrthoInspector	1	1.000	-	-		oto93625
orthoMCL	1	0.900	-	-		OOG6_106086
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4693
SonicParanoid	1	1.000	-	-		X5814
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790