Protein Alignment Npc2a and npc2.1

DIOPT Version :9

• Sequence 1: NP_608637.1
• Gene: Npc2a / 33374
• FlyBaseID: FBgn0031381
• Length: 148
• Species: Drosophila melanogaster
• Sequence 2: NP_775331.1
• Gene: npc2.1 / 282673
• ZFINID: ZDB-GENE-021206-13
• Length: 149
• Species: Danio rerio
• Alignment Length: 147
• Identity: 49/147 - (33%)
• Similarity: 80/147 - (54%)
• Gaps: 9/147 - (6%)

  Fly     1 MLRYAVIACAALVVFAGALEFSDCGSKTGKFTRVAIEGCDTTKAECILKRNTTVSFSIDFALAEE 65
            :|.:....|      |..::|.||||..||..:|.|:.|  ::..|.|.:..:.:.::.|:...|
Zfish    10 LLSFLAYTC------ADPVKFVDCGSVDGKVVQVDIKPC--SQQPCKLHKGQSYTVNVTFSSGVE 66

  Fly    66 ATAVKTVVHGKVLGIEMPFPLANPDACVDSGLKCPLEKDESYRYTATLPVLRSYPKVSVLVKWEL 130
            :...|.||||.:.|:.:|||:...|.| .||::||:...:.|.|...|||...||.:.|:|:|||
Zfish    67 SQTSKAVVHGVLAGVPVPFPIPIDDGC-KSGIQCPIVPQKPYNYVTELPVKTEYPAIKVVVEWEL 130

  Fly   131 QDQDGADIICVEIPAKI 147
            :|....|:.|::.|.:|
Zfish   131 RDDSSKDLFCIKFPVQI 147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npc2a	NP_608637.1	Npc2_like	21..145	CDD:238458	44/123 (36%)
npc2.1	NP_775331.1	Npc2_like	24..145	CDD:238458	44/123 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583274
Domainoid	1	1.000	101	1.000	Domainoid score	I6909
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4697
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4963
OMA	1	1.010	-	-		QHG49115
OrthoDB	1	1.010	-	-		D1612792at2759
OrthoFinder	1	1.000	-	-		FOG0007859
OrthoInspector	1	1.000	-	-		otm24240
orthoMCL	1	0.900	-	-		OOG6_106086
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4693
SonicParanoid	1	1.000	-	-		X5814
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800