Protein Alignment Npc2a and NPC2

DIOPT Version :9

• Sequence 1: NP_608637.1
• Gene: Npc2a / 33374
• FlyBaseID: FBgn0031381
• Length: 148
• Species: Drosophila melanogaster
• Sequence 2: NP_001350617.1
• Gene: NPC2 / 10577
• HGNCID: 14537
• Length: 174
• Species: Homo sapiens
• Alignment Length: 132
• Identity: 49/132 - (37%)
• Similarity: 76/132 - (57%)
• Gaps: 3/132 - (2%)

  Fly    16 AGALEFSDCGSKTGKFTRVAIEGCDTTKAECILKRNTTVSFSIDFALAEEATAVKTVVHGKVLGI 80
            |..::|.||||..|....|.:..|.|  ..|.|.:..:.|.::.|....::.:.|.||||.::|:
Human    19 AEPVQFKDCGSVDGVIKEVNVSPCPT--QPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGV 81

  Fly    81 EMPFPLANPDACVDSGLKCPLEKDESYRYTATLPVLRSYPKVSVLVKWELQDQDGADIICVEIPA 145
            .:|||:..||.| .||:.||::||::|.|...|||...||.:.::|:|:|||.....:.|.|||.
Human    82 PVPFPIPEPDGC-KSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPV 145

  Fly   146 KI 147
            :|
Human   146 QI 147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npc2a	NP_608637.1	Npc2_like	21..145	CDD:238458	46/123 (37%)
NPC2	NP_001350617.1	Npc2_like	24..145	CDD:238458	46/123 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149211
Domainoid	1	1.000	106	1.000	Domainoid score	I6614
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4697
Inparanoid	1	1.050	106	1.000	Inparanoid score	I4945
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49115
OrthoDB	1	1.010	-	-		D1612792at2759
OrthoFinder	1	1.000	-	-		FOG0007859
OrthoInspector	1	1.000	-	-		oto90049
orthoMCL	1	0.900	-	-		OOG6_106086
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4693
SonicParanoid	1	1.000	-	-		X5814
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800