Protein Alignment Npc2a and NPC2

DIOPT Version :10

• Sequence 1: NP_608637.1
• Gene: Npc2a / 33374
• FlyBaseID: FBgn0031381
• Length: 148
• Species: Drosophila melanogaster
• Sequence 2: NP_001350617.1
• Gene: NPC2 / 10577
• HGNCID: 14537
• Length: 174
• Species: Homo sapiens
• Alignment Length: 132
• Identity: 49/132 - (37%)
• Similarity: 76/132 - (57%)
• Gaps: 3/132 - (2%)

  Fly    16 AGALEFSDCGSKTGKFTRVAIEGCDTTKAECILKRNTTVSFSIDFALAEEATAVKTVVHGKVLGI 80
            |..::|.||||..|....|.:..|.|  ..|.|.:..:.|.::.|....::.:.|.||||.::|:
Human    19 AEPVQFKDCGSVDGVIKEVNVSPCPT--QPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGV 81

  Fly    81 EMPFPLANPDACVDSGLKCPLEKDESYRYTATLPVLRSYPKVSVLVKWELQDQDGADIICVEIPA 145
            .:|||:..||.| .||:.||::||::|.|...|||...||.:.::|:|:|||.....:.|.|||.
Human    82 PVPFPIPEPDGC-KSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPV 145

  Fly   146 KI 147
            :|
Human   146 QI 147

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Npc2a	NP_608637.1	Npc2_like	21..145	CDD:238458	46/123 (37%)
NPC2	NP_001350617.1	Npc2_like	24..145	CDD:238458	46/123 (37%)