Protein Alignment Got2 and AAT1

DIOPT Version :9

• Sequence 1: NP_722745.1
• Gene: Got2 / 33373
• FlyBaseID: FBgn0001125
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_012816.1
• Gene: AAT1 / 853755
• SGDID: S000001589
• Length: 451
• Species: Saccharomyces cerevisiae
• Alignment Length: 453
• Identity: 171/453 - (37%)
• Similarity: 241/453 - (53%)
• Gaps: 58/453 - (12%)

  Fly    26 RANRVSTW-------FSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVRE 83
            |....|.|       .|.|...|||.:||::|.|||..|..||:|..|.|:|...:....|||.:
Yeast     5 RLTNCSLWRPYYTSSLSRVPRAPPDKVLGLSEHFKKVKNVNKIDLTVGIYKDGWGKVTTFPSVAK 69

  Fly    84 AEKRVVSR-SLDK--EYATIIGIPEFYNKAIELALGK-----GSKRLAAKHNVTAQSISGTGALR 140
            |:|.:.|. .|:|  .|..|.|..||....::....:     |...||.......|::||||||.
Yeast    70 AQKLIESHLELNKNLSYLPITGSKEFQENVMKFLFKESCPQFGPFYLAHDRISFVQTLSGTGALA 134

  Fly   141 IGAAFLAKFWQGNREIYIPSPSWGNHVAIFEHAGLPVNRYRY-YDKDTCALDFGGLIEDLKKIPE 204
            :.|.|||.|.  :|:|:||.|||.||..||::.|.. |.||| |.||. .:|..|.||.||....
Yeast   135 VAAKFLALFI--SRDIWIPDPSWANHKNIFQNNGFE-NIYRYSYYKDG-QIDIDGWIEQLKTFAY 195

  Fly   205 KS---------IVLLHACAHNPTGVDPTLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQ 260
            .:         .::||||.|||||:|||.|||.:|...:.:..:.|.:||||||..:|::.:||.
Yeast   196 NNQQENNKNPPCIILHACCHNPTGLDPTKEQWEKIIDTIYELKMVPIVDMAYQGLESGNLLKDAY 260

  Fly   261 AVR------TFEADGHDFCLAQSFAKNMGLYGERAGAFTVLCSDEEEAAR-------------VM 306
            .:|      .:....:...|.|||||||||||||.|:.:|:........:             :.
Yeast   261 LLRLCLNVNKYPNWSNGIFLCQSFAKNMGLYGERVGSLSVITPATANNGKFNPLQQKNSLQQNID 325

  Fly   307 SQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRIIDVRTKLKDNLIKLGSSQN 371
            ||:|.::||:||:||.:|:|:...:|::..|:.||.|||..|..|:..||.::.|.|       .
Yeast   326 SQLKKIVRGMYSSPPGYGSRVVNVVLSDFKLKQQWFKDVDFMVQRLHHVRQEMFDRL-------G 383

  Fly   372 WDHIVN---QIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSKNVEYLAESIHKVTK 431
            |..:||   |.|||.:|...|:||:.|..::.||||.|||:|::||...||:||.||:..|:|
Yeast   384 WPDLVNFAQQHGMFYYTRFSPKQVEILRNNYFVYLTGDGRLSLSGVNDSNVDYLCESLEAVSK 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Got2	NP_722745.1	AAT_I	21..431	CDD:302748	170/451 (38%)
		Aminotran_1_2	58..426	CDD:278580	153/407 (38%)
AAT1	NP_012816.1	TyrB	21..445	CDD:224365	166/434 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341993
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62835
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11879
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.810