DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Got2 and ASP1

DIOPT Version :9

Sequence 1:	NP_722745.1	Gene:	Got2 / 33373	FlyBaseID:	FBgn0001125	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_001118421.1	Gene:	ASP1 / 817648	AraportID:	AT2G30970	Length:	430	Species:	Arabidopsis thaliana

Alignment Length:	402	Identity:	209/402 - (51%)
Similarity:	285/402 - (70%)	Gaps:	2/402 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 VSTWFSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAEKRVVSRSLD 94
            :|:|:..|:..|.|.||||||||..|.:|:|:|:|.|||||||.:|.||..|||||||:.. |..
plant    29 MSSWWKSVEPAPKDPILGVTEAFLADPSPEKVNVGVGAYRDDNGKPVVLECVREAEKRLAG-STF 92

  Fly    95 KEYATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKFWQGNREIYIP 159
            .||..:.|..:..:..::||.|..|:.:..|.....|::|||||.|:.|.|..:|..|: :||||
plant    93 MEYLPMGGSAKMVDLTLKLAYGDNSEFIKDKRIAAVQTLSGTGACRLFADFQKRFSPGS-QIYIP 156

  Fly   160 SPSWGNHVAIFEHAGLPVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACAHNPTGVDPTL 224
            .|:|.||..|::.|.:|...|.||..:|..|||..|::|:|..||.|..|||||||||||||||.
plant   157 VPTWSNHHNIWKDAQVPQKTYHYYHPETKGLDFSALMDDVKNAPEGSFFLLHACAHNPTGVDPTE 221

  Fly   225 EQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFAKNMGLYGERA 289
            |||||||.|.|.:..:.|.||||||||:||..|||:::|.|..|||...::||:||||||||:|.
plant   222 EQWREISQLFKAKKHFAFFDMAYQGFASGDPARDAKSIRIFLEDGHHIGISQSYAKNMGLYGQRV 286

  Fly   290 GAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRIID 354
            |..:|||.|.::|..|.||::.|.|.:|||||:|||::.:.||.:.:|::.|||:||:||||||.
plant   287 GCLSVLCEDPKQAVAVKSQLQQLARPMYSNPPLHGAQLVSTILEDPELKSLWLKEVKVMADRIIG 351

  Fly   355 VRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSKNV 419
            :||.|:::|.||||..:|:|:..||||||::||.||||.:|..::.:|:|.:||:||||||:.||
plant   352 MRTTLRESLEKLGSPLSWEHVTKQIGMFCYSGLTPEQVDRLTSEYHIYMTRNGRISMAGVTTGNV 416

  Fly   420 EYLAESIHKVTK 431
            .|||.:||:|||
plant   417 GYLANAIHEVTK 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Got2	NP_722745.1	AAT_I	21..431	CDD:302748	207/400 (52%)
Got2	NP_722745.1	Aminotran_1_2	58..426	CDD:278580	190/367 (52%)
ASP1	NP_001118421.1	PLN02397	10..429	CDD:215222	209/402 (52%)
ASP1	NP_001118421.1	Aminotran_1_2	57..423	CDD:278580	190/367 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	387	1.000	Domainoid score	I155
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1572
Inparanoid	1	1.050	426	1.000	Inparanoid score	I427
OMA	1	1.010	-	-		QHG62835
OrthoDB	1	1.010	-	-		D1104596at2759
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	1	1.000	-	-		oto3301
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	1	1.100	-	-	LDO	PTHR11879
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X428
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840