Protein Alignment Got2 and GOT1

DIOPT Version :10

• Sequence 1: NP_722745.1
• Gene: Got2 / 33373
• FlyBaseID: FBgn0001125
• Length: 431
• Species: Drosophila melanogaster
• Sequence 2: NP_002070.1
• Gene: GOT1 / 2805
• HGNCID: 4432
• Length: 413
• Species: Homo sapiens
• Alignment Length: 405
• Identity: 192/405 - (47%)
• Similarity: 279/405 - (68%)
• Gaps: 7/405 - (1%)

  Fly    34 FSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAEKRVVS-RSLDKEY 97
            |:||....|..:..:|..|::|.:|:|:|||.||||.|:..|:|||.|::.|:::.: .||:.||
Human     7 FAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIANDNSLNHEY 71

  Fly    98 ATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKFWQG----NREIYI 158
            ..|:|:.||.:.|..||||..|..|..|.....||:.|||||||||.|||:::.|    |..:|:
Human    72 LPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWYNGTNNKNTPVYV 136

  Fly   159 PSPSWGNHVAIFEHAGL-PVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACAHNPTGVDP 222
            .||:|.||.|:|..||. .:..|||:|.:...||..|.:.||:..||.|||:||||||||||:||
Human   137 SSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIVVLHACAHNPTGIDP 201

  Fly   223 TLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFAKNMGLYGE 287
            |.|||::|::::|.|.|:||.|.||||||:|:::|||.|:|.|.::|.:|..||||:||.|||.|
Human   202 TPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYFVSEGFEFFCAQSFSKNFGLYNE 266

  Fly   288 RAGAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRI 352
            |.|..||:..:.|...:|:||::.::|..:||||..||||.|..|:|.:|..:|..:||.|||||
Human   267 RVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRI 331

  Fly   353 IDVRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSK 417
            :.:|::|:..|..|.:...|:||.:|||||.||||.|:||:.|:.:..:||...||::::|:|:|
Human   332 LTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTK 396

  Fly   418 NVEYLAESIHK-VTK 431
            |::|:|.|||: |||
Human   397 NLDYVATSIHEAVTK 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Got2	NP_722745.1	AAT_I	21..431	CDD:450240	190/403 (47%)
GOT1	NP_002070.1	PTZ00376	5..412	CDD:240390	192/405 (47%)