DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Got2 and SPAC10F6.13c

DIOPT Version :9

Sequence 1:	NP_722745.1	Gene:	Got2 / 33373	FlyBaseID:	FBgn0001125	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_593264.1	Gene:	SPAC10F6.13c / 2543020	PomBaseID:	SPAC10F6.13c	Length:	409	Species:	Schizosaccharomyces pombe

Alignment Length:	402	Identity:	172/402 - (42%)
Similarity:	257/402 - (63%)	Gaps:	5/402 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAEKRVVSR-SLDKEY 97
            |:.::....|||..:...:.:|.:|||:|:..||||||..:|::||:|::|.|.|..: |.:.||
pombe     6 FANIEEAKADAIFKLNAQYHQDEDPKKVNMSVGAYRDDTGKPWILPAVKKASKIVEEQASFNHEY 70

  Fly    98 ATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKFW--QGNREIYIPS 160
            ..|.|:|.|...|.|:........|:.....:.||:|||||..:.|:|:..|:  .....:||.:
pombe    71 LPIAGLPRFTKAAAEVLFRPNPHLLSEDRVASMQSVSGTGANFLAASFIETFYVKHTGAHVYISN 135

  Fly   161 PSWGNHVAIFEHAGLPVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACAHNPTGVDPTLE 225
            |:|..|..::|..|:.|:.|.|:|....:.|:.|::..:|..||.||.|||||||||||:|||.|
pombe   136 PTWPVHRTLWEKLGVTVDTYPYWDAKNRSFDYEGMLSTIKSAPEGSIFLLHACAHNPTGIDPTRE 200

  Fly   226 QWREI-SALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFAKNMGLYGERA 289
            ||..| .:|:.:::|..| |:||||||:||::||:.|:..|.....||.:.|||||||||||||.
pombe   201 QWLSIFESLLSRKHLVVF-DIAYQGFASGDLNRDSWALNEFVKYNKDFFVCQSFAKNMGLYGERT 264

  Fly   290 GAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMADRIID 354
            |....:..|.....:|:||:.|:.|...||||.:||||||||||:..|.|:|.:|:|.|:.|||:
pombe   265 GCMHYVAKDASTKNKVLSQLCIVQRNTISNPPAYGARIAAEILNSPQLFAEWEQDLKTMSSRIIE 329

  Fly   355 VRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVTSKNV 419
            :|.:|:|:|:.|.:..:||||..|||||.||||.|.|||...:.:.:|.:.:||:||||:.:.||
pombe   330 MRKRLRDSLVALKTPGSWDHITQQIGMFSFTGLTPAQVQFCQERYHLYFSANGRISMAGLNNSNV 394

  Fly   420 EYLAESIHKVTK 431
            |::|::.:...:
pombe   395 EHVAQAFNHAVR 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Got2	NP_722745.1	AAT_I	21..431	CDD:302748	172/400 (43%)
Got2	NP_722745.1	Aminotran_1_2	58..426	CDD:278580	167/371 (45%)
SPAC10F6.13c	NP_593264.1	TyrB	5..405	CDD:224365	172/399 (43%)
SPAC10F6.13c	NP_593264.1	Aminotran_1_2	30..401	CDD:278580	167/371 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62835
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X428
TreeFam	0	0.000	Not matched by this tool.
	6	5.720