DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Got2 and SPBC725.01

DIOPT Version :9

Sequence 1:	NP_722745.1	Gene:	Got2 / 33373	FlyBaseID:	FBgn0001125	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_595481.1	Gene:	SPBC725.01 / 2541186	PomBaseID:	SPBC725.01	Length:	437	Species:	Schizosaccharomyces pombe

Alignment Length:	410	Identity:	221/410 - (53%)
Similarity:	288/410 - (70%)	Gaps:	6/410 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 CRANRVSTWF---SEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAEK 86
            |.|::....|   ::|.|||||.|.|:|||:|||.:.||:|||||.||||..:|:||||||:||.
pombe    28 CLASQSKRGFKVWADVPMGPPDPIFGITEAYKKDGDVKKMNLGAGTYRDDAGKPYVLPSVRQAET 92

  Fly    87 RVVSRSLDKEYATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKFWQ 151
            .::|:.||||||.|.|||.|..:|.:||.|...:.:..: .|:||||||||||.|.|.|||.|:.
pombe    93 ELLSQKLDKEYAPITGIPSFRVQATKLAYGDVYESIKDR-LVSAQSISGTGALCIAANFLASFYP 156

  Fly   152 GNREIYIPSPSWGNHVAIFEHAGLPVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACAHN 216
             ::.||:..|:||||..:|..|||.|..|:|||..|..||..|::.||...|:.||:||||||||
pombe   157 -SKTIYVSDPTWGNHKNVFSRAGLTVKSYKYYDPATRGLDIKGMLSDLTSAPDGSIILLHACAHN 220

  Fly   217 PTGVDPTLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFAKN 281
            |||||||..||.:|...::|:|.:..:||||||||:||..|||.|.|.|.:......|.||||||
pombe   221 PTGVDPTKAQWDDILKTMQKKNHFALLDMAYQGFASGDFARDAYATRLFASSNVPMLLCQSFAKN 285

  Fly   282 MGLYGERAGAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVK 346
            |||||||||.|::|.:|.|||||:.||.|||||.|||||||:|||||..||:|..||.||..:|.
pombe   286 MGLYGERAGCFSILANDAEEAARIESQTKILIRALYSNPPVNGARIANHILSNPALREQWAGEVV 350

  Fly   347 LMADRIIDVRTKLKDNLIK-LGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVS 410
            .|::|:..:|..|::.|.| |.:..:|.||.:||||||:|||.|:||..|.|.:.:|||.:||:|
pombe   351 GMSERLKSMRKALRNILEKDLKNKHSWKHITDQIGMFCYTGLNPQQVDVLAKQYHIYLTKNGRIS 415

  Fly   411 MAGVTSKNVEYLAESIHKVT 430
            ::|:.:.||.|.||:|:.||
pombe   416 ISGLNTSNVRYFAEAINAVT 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Got2	NP_722745.1	AAT_I	21..431	CDD:302748	221/410 (54%)
Got2	NP_722745.1	Aminotran_1_2	58..426	CDD:278580	201/368 (55%)
SPBC725.01	NP_595481.1	PTZ00376	37..437	CDD:240390	219/401 (55%)
SPBC725.01	NP_595481.1	Aminotran_1_2	64..431	CDD:278580	201/368 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	394	1.000	Domainoid score	I113
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1572
Inparanoid	1	1.050	428	1.000	Inparanoid score	I328
OMA	1	1.010	-	-		QHG62835
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	1	1.000	-	-		oto101060
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	1	1.100	-	-	LDO	PTHR11879
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X428
TreeFam	1	0.960	-	-
	13	12.830