DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Got2 and Got1

DIOPT Version :9

Sequence 1:	NP_722745.1	Gene:	Got2 / 33373	FlyBaseID:	FBgn0001125	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_036703.2	Gene:	Got1 / 24401	RGDID:	2721	Length:	413	Species:	Rattus norvegicus

Alignment Length:	407	Identity:	187/407 - (45%)
Similarity:	274/407 - (67%)	Gaps:	7/407 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TWFSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREAEKRVVS-RSLDK 95
            ::|::|...||..:..:...|:.|.:|:|:|||.||||.|::||:|||.||:.|:::.: .||:.
  Rat     5 SFFAQVPQAPPVLVFKLIADFRDDPDPRKVNLGVGAYRTDDSQPWVLPVVRKVEQKIANDHSLNH 69

  Fly    96 EYATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKFWQG----NREI 156
            ||..|:|:.||.:.|.:|.||..|..|........||:.|||||||||.||.:::.|    |..:
  Rat    70 EYLPILGLAEFRSCASQLVLGDNSPALRENRVGGVQSLGGTGALRIGADFLGRWYNGTDNKNTPV 134

  Fly   157 YIPSPSWGNHVAIFEHAGL-PVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACAHNPTGV 220
            |:.||:|.||..:|..||. .:..|||:|.:...||..|.:.||:..||.||.:||||||||||.
  Rat   135 YVSSPTWENHNGVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEFSIFVLHACAHNPTGT 199

  Fly   221 DPTLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFAKNMGLY 285
            |||.|:|::|:|::|:|.|:||.|.||||||:||:::||.|:|.|.::|.:...||||:||.|||
  Rat   200 DPTEEEWKQIAAVMKRRFLFPFFDSAYQGFASGDLEKDAWAIRYFVSEGFELFCAQSFSKNFGLY 264

  Fly   286 GERAGAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKDVKLMAD 350
            .||.|..||:..:.:...||:||::.::|..:||||..||||.|..|:|.:|..:|..:||.|||
  Rat   265 NERVGNLTVVGKEHDSVLRVLSQMEKIVRITWSNPPAQGARIVATTLSNPELFKEWKGNVKTMAD 329

  Fly   351 RIIDVRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRVSMAGVT 415
            ||:.:|::|:..|..|.:...|.||..|||||.||||.|:||:.|:.:..:||...||::|.|:|
  Rat   330 RILTMRSELRARLEALKTPGTWSHITEQIGMFSFTGLNPKQVEYLVNEKHIYLMPSGRINMCGLT 394

  Fly   416 SKNVEYLAESIHK-VTK 431
            :||::|:|.||:: |||
  Rat   395 TKNLDYVATSINEAVTK 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Got2	NP_722745.1	AAT_I	21..431	CDD:302748	185/405 (46%)
Got2	NP_722745.1	Aminotran_1_2	58..426	CDD:278580	176/373 (47%)
Got1	NP_036703.2	PTZ00376	5..411	CDD:240390	185/405 (46%)
Got1	NP_036703.2	Aminotran_1_2	31..405	CDD:278580	176/373 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62835
OrthoDB	1	1.010	-	-		D1104596at2759
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X428
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730