DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Got2 and Got2

DIOPT Version :9

Sequence 1:	NP_722745.1	Gene:	Got2 / 33373	FlyBaseID:	FBgn0001125	Length:	431	Species:	Drosophila melanogaster
Sequence 2:	NP_034455.1	Gene:	Got2 / 14719	MGIID:	95792	Length:	430	Species:	Mus musculus

Alignment Length:	412	Identity:	261/412 - (63%)
Similarity:	328/412 - (79%)	Gaps:	0/412 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 PGERMCRANRVSTWFSEVQMGPPDAILGVTEAFKKDTNPKKINLGAGAYRDDNTQPFVLPSVREA 84
            ||.....:.|.|:|::.|:|||||.|||||||||:|||.||:|||.|||||||.:|:||||||:|
Mouse    19 PGLAAAASARASSWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKA 83

  Fly    85 EKRVVSRSLDKEYATIIGIPEFYNKAIELALGKGSKRLAAKHNVTAQSISGTGALRIGAAFLAKF 149
            |.::.:::|||||..|.|:.||...:.|||||:.::.|.:...||.|:||||||||:||:||.:|
Mouse    84 EAQIAAKNLDKEYLPIGGLAEFCKASAELALGENNEVLKSGRFVTVQTISGTGALRVGASFLQRF 148

  Fly   150 WQGNREIYIPSPSWGNHVAIFEHAGLPVNRYRYYDKDTCALDFGGLIEDLKKIPEKSIVLLHACA 214
            ::.:|::::|.||||||..||..||:.:..|||||..||..||.|.:||:.||||:|::||||||
Mouse   149 FKFSRDVFLPKPSWGNHTPIFRDAGMQLQGYRYYDPKTCGFDFSGALEDISKIPEQSVLLLHACA 213

  Fly   215 HNPTGVDPTLEQWREISALVKKRNLYPFIDMAYQGFATGDIDRDAQAVRTFEADGHDFCLAQSFA 279
            ||||||||..|||:||:::|||:||:.|.||||||||:||.|:||.|||.|...|.:.||.||:|
Mouse   214 HNPTGVDPRPEQWKEIASVVKKKNLFAFFDMAYQGFASGDGDKDAWAVRHFIEQGINVCLCQSYA 278

  Fly   280 KNMGLYGERAGAFTVLCSDEEEAARVMSQVKILIRGLYSNPPVHGARIAAEILNNEDLRAQWLKD 344
            |||||||||.|||||:|.|.|||.||.||:|||||.||||||::||||||.||.:.|||.|||::
Mouse   279 KNMGLYGERVGAFTVVCKDAEEAKRVESQLKILIRPLYSNPPLNGARIAATILTSPDLRKQWLQE 343

  Fly   345 VKLMADRIIDVRTKLKDNLIKLGSSQNWDHIVNQIGMFCFTGLKPEQVQKLIKDHSVYLTNDGRV 409
            ||.||||||.:||:|..||.|.|||.||.||.:|||||||||||||||::|.|:.|||:|.|||:
Mouse   344 VKGMADRIISMRTQLVSNLKKEGSSHNWQHITDQIGMFCFTGLKPEQVERLTKEFSVYMTKDGRI 408

  Fly   410 SMAGVTSKNVEYLAESIHKVTK 431
            |:|||||.||.|||.:||:|||
Mouse   409 SVAGVTSGNVGYLAHAIHQVTK 430

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Got2	NP_722745.1	AAT_I	21..431	CDD:302748	258/409 (63%)
Got2	NP_722745.1	Aminotran_1_2	58..426	CDD:278580	233/367 (63%)
Got2	NP_034455.1	PLN02397	32..430	CDD:215222	255/397 (64%)
Got2	NP_034455.1	Aminotran_1_2	57..425	CDD:278580	233/367 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833310
Domainoid	1	1.000	487	1.000	Domainoid score	I388
eggNOG	1	0.900	-	-		E1_COG1448
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1572
Inparanoid	1	1.050	545	1.000	Inparanoid score	I1147
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62835
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000707
OrthoInspector	1	1.000	-	-		oto93143
orthoMCL	1	0.900	-	-		OOG6_100337
Panther	1	1.100	-	-	LDO	PTHR11879
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X428
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.760