Protein Alignment CG7289 and C17H12.2

DIOPT Version :9

• Sequence 1: NP_608635.1
• Gene: CG7289 / 33372
• FlyBaseID: FBgn0031379
• Length: 637
• Species: Drosophila melanogaster
• Sequence 2: NP_501039.1
• Gene: C17H12.2 / 177441
• WormBaseID: WBGene00015928
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 648
• Identity: 195/648 - (30%)
• Similarity: 317/648 - (48%)
• Gaps: 114/648 - (17%)

  Fly    16 MRRMKRLAEGTISSYRRLFLLLLCVCVVFYMIPPIFRYIF---LSAPEQKDPHSMCMDDRLTPFI 77
            ||.::|..:      |||.::   :.||.::|     :||   .|:.........|..::|..:.
 Worm    23 MRMVRRYPK------RRLAII---IGVVLFVI-----FIFSRGTSSGTSFTKQHQCSAEKLKLWE 73

  Fly    78 LQNFEFDANIRHVSPAKMPGERDFTPYVGNGYLGLEIAHDAFLNIKNGRAMQLPIPFQPVVSVSG 142
            .:..|||..|.:.|          ..:|||||:|::......:..|| |.:.:...|.|.:::.
 Worm    74 KEIDEFDTGINNQS----------VEFVGNGYIGVDSFGQLRVQEKN-RVLDVETNFYPGLNIE- 126

  Fly   143 GSASGGEKEATV---VEYLTGMVHRFQCFA--GYFVSYT--YYAHRTQPNIFMQELQITN-TRNL 199
               ..|::...|   .::..|:....:||:  |.....|  .:||||:||.|:|.:|::| |::.
 Worm   127 ---IDGQQPVEVTKMTDFKNGIFKILRCFSMDGECACVTSQIWAHRTRPNYFVQLIQVSNPTKST 188

  Fly   200 LEDIELIMPRVNLQKLTRRTVPLSEPVSVGVFTYTELEVLSGTV-QLQAENPSKSIVISIV--KP 261
            :        |:||.:|           |...:.:::|..|  || |.|....|.::|.:..  |.
 Worm   189 V--------RLNLSRL-----------SSNWWAHSKLGEL--TVHQRQVARASYAVVCTDAPGKV 232

  Fly   262 QMDSKLQLRKRGTVRIVYPTAVHYSKPVAEEKIGGISETIEQQATQAMAKLLQKLGSKPSNPGSL 326
            .:..|.:...|.|..|.       |||.:||            |::...:..|  ..|.|.  :|
 Worm   233 SVSQKREESFRFTCSIA-------SKPTSEE------------ASRDAIRFFQ--SGKDSK--TL 274

  Fly   327 NSVNIYRQEHIDVWTDLWATGFTISTSKAENSLNGDRINATMYAVLSQVRSFEFEEAGGSKK--- 388
            :|      ||.|.|:.:..|||:::.|||.|:|||||||||.|.::|.:|:...|.....:.
 Worm   275 DS------EHFDGWSKMHLTGFSVANSKAPNTLNGDRINATKYILMSNLRAPTIEHGATLESVKP 333

  Fly   389 -EDIAKALTYAEGCYDSY-HTLQAENLWREMSNLQQLNSLVTSWMLTLEKQGCHNLIRAGASGVI 451
             |::|:.   :|.||..: :.|....||::.....:|..||.:||||.:|:||:||:..||.|..
 Worm   334 LENLARK---SELCYTGHSNLLFPSRLWQDWDTPTKLFELVNTWMLTFQKRGCNNLLSTGAIGAS 395

  Fly   452 QAMVLSFGSFRFSNQHLECNIHPKFLHRDFHFRRL----NYGNKTHVNVTIIVDDDNKAVINIAL 512
            ||.|.|..:..:.:.|||..:....|||:.:|..:    |.|....:.|.|.:|.:|:....::
 Worm   396 QAFVQSLTASSYHDSHLEVALDAHDLHREMNFHGIPVYSNMGVVGTIRVDIKLDTENRPYFMVS- 459

  Fly   513 DRSDRSYYACDGGCLDEPVLLTQNRRQFPVKLTEPLTAILYITEDKQHMEELHHAIHVKEVVEAP 577
              |....:.|||||||.||.|.:...|.|||:|:|:|::|||...::|:|.|.:||||.||..||
 Worm   460 --SSSQLFVCDGGCLDSPVSLGKTPVQLPVKVTKPVTSLLYIAPSRRHLELLRNAIHVSEVGAAP 522

  Fly   578 AHEQHLIALHRHGHQLGGLPTLFWVSVCAIIIVFHIFLCKLIIKEYCEP-----SDKLRYRYN 635
            |||:.:|.:||.|...||: |.|||.|..:::.||:.:.|::..|:.:.     :..||.||:
 Worm   523 AHEEEVIEMHRSGESTGGM-TTFWVFVFVVVVAFHLVVAKIVWSEWRKGDMTPYNPYLRNRYS 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7289	NP_608635.1	DUF2152	18..635	CDD:287225	192/644 (30%)
C17H12.2	NP_501039.1	DUF2152	13..586	CDD:287225	195/648 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162550
Domainoid	1	1.000	232	1.000	Domainoid score	I1376
eggNOG	1	0.900	-	-		E1_KOG3778
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12668
Inparanoid	1	1.050	231	1.000	Inparanoid score	I2185
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28650
OrthoDB	1	1.010	-	-		D378033at33208
OrthoFinder	1	1.000	-	-		FOG0006028
OrthoInspector	1	1.000	-	-		oto17208
orthoMCL	1	0.900	-	-		OOG6_107711
Panther	1	1.100	-	-	LDO	PTHR31386
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3545
SonicParanoid	1	1.000	-	-		X4325
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.840