Protein Alignment CG15356 and Emsy

DIOPT Version :9

• Sequence 1: NP_608633.1
• Gene: CG15356 / 33370
• FlyBaseID: FBgn0031377
• Length: 1023
• Species: Drosophila melanogaster
• Sequence 2: XP_006229864.1
• Gene: Emsy / 361607
• RGDID: 1310712
• Length: 1351
• Species: Rattus norvegicus
• Alignment Length: 1170
• Identity: 288/1170 - (24%)
• Similarity: 430/1170 - (36%)
• Gaps: 401/1170 - (34%)

  Fly     1 MWPQTLEMSRDECRGMLRRLELESYSHVVSVFRAQGALSETKAKLLEELRQQFHINQERHRAEVR 65
            :||..|::|||||:.:||:||||:|:.|:|..||||.|::.|..||.||.:...|:.||||||||
  Rat     4 VWPTLLDLSRDECKRILRKLELEAYAGVISALRAQGDLTKEKKDLLGELSKVLSISTERHRAEVR 68

  Fly    66 RAANDEQLCTIAE--------------NVCGPNTWQEWSREGRRLYPLLPRISPQTALSIVANDL 116
            ||.|||:|.|||.              ::.|||:..|||.|||||.||:||:.||||.::.||.:
  Rat    69 RAVNDERLTTIAHKMNLSLYLGERPSYSMSGPNSSSEWSIEGRRLVPLMPRLVPQTAFTVTANAV 133

  Fly   117 AAKACEENAKLAAPAETA-----VHFG---------EALVEQASLMSLKYPRGARIQDTAMVIMA 167
            |..|.:.||.|..|||||     |.:.         ...|...|:.::|.||.|....:.:|
  Rat   134 ANAAVQHNASLPVPAETASKEVVVCYSYTSTTSTPTSTPVPSGSIATVKSPRPASPASSVVV--- 195

  Fly   168 EPFKVPDLPNEVKKMTQKRKENDSGIDGKPNKKRHMQQPHPQQPHLQASQQQQQSQQLNPNSSNP 232
                   ||:......:....:|.  |.||.|:|                      :.|.:||:|
  Rat   196 -------LPSGSTVYVKSVSCSDE--DEKPRKRR----------------------RTNSSSSSP 229

  Fly   233 GMEEADP---VPPEKRMTARTLQQRYFYQQQMKHKQRLAS-KRNLANRL-----------GSPSA 282
            .:.:..|   ||..|.:|.           .:....:::: .:::||.|           ..||.
  Rat   230 VVLKEVPKAVVPVSKTITV-----------PVSGSPKMSNIMQSIANSLPPHMSPVKITFTKPST 283

  Fly   283 QSGNPLGGRNMPSSGGDTSTAKRSAAPAKSGRRAQKQLQQQQKLQQHQQQKVLM----QSQETVP 343
            |:.|             |:|                             |||::    .|...||
  Rat   284 QTTN-------------TTT-----------------------------QKVIIVTTSPSSTFVP 306

  Fly   344 NHMVVQPHVEYVLDEALKTLAASNPPTPTSTVA-----PPYTILNEPRPLVTLKPLKTIKPMIYG 403
            |          :|.:: ...||.....|||.:|     ||..|......|||
  Rat   307 N----------ILSKS-HNYAAVTKLVPTSVIASTTQKPPVVITASQASLVT------------- 347

  Fly   404 PQSGMPSAEIGSPTTPGSRGFANSPIVFKEKLQASP-VQVATQGQGSPTKKFVAEERHADAMPSA 467
                  |:..|:..:..|.  .:|.:.....:.::| |.::|..||..|...........:..|.
  Rat   348 ------SSSNGNSNSTSSS--ISSTVAVTAVVSSTPSVVMSTVAQGVSTSAIKVASTRLPSPKSL 404

  Fly   468 ATTPTPISTANLPLAPQII---SVQKIP--APSMGGKLRAAVASPTSSTNS-------------- 513
            .:.||.| .|..|...|..   .:|::|  .|..|       |.|:|.:..
  Rat   405 VSGPTQI-LAQFPKQHQQSPKQQLQQVPPQTPQPG-------AQPSSVSQQQQQQQQQQQQQQQQ 461

  Fly   514 ------------TLLPPGAKTT-----PKKFNILEGDAKPKTLPSSAVRLLPYTEPIGGPLSPLK 561
                        :.||||.|.|     .....|:....:|.       ::||  :|:...|
  Rat   462 QQQQQQQQQPQHSPLPPGIKPTIQIKQESGVKIITQQVQPS-------KILP--KPVTATL---- 513

  Fly   562 DSRVTPLSSASTVNIIKNIPASSLNNTLITPLPSAGTTMPANLFRAKVTPSIKGASGAAGGATVI 626
                 |.||.|.:.::     ||....:.|.|.:..|...|...|..|:||:...:...|.||.
  Rat   514 -----PTSSNSPIMVV-----SSNGAIMTTKLVTTPTGTQATYTRPTVSPSLGRVATTPGAATY- 567

  Fly   627 GAAGATGIGGAGAGPQILGNIKLTSSSGGAATIKQVPSSALRNIKICSPNGKLFLQPGKLPAGSI 691
                                :|.||.|    .|..||.|      :.:..||:.
  Rat   568 --------------------VKTTSGS----IITVVPKS------LATLGGKII----------- 591

  Fly   692 IHKFNNASSTAVSAAGGVVTTTTTTVSPTKQPAREQRISIQKILQPATGSASSGSSSPTTTTTTI 756
                   ||..||.    .||..||:..|.:|   ..|.:||    .||..           |||
  Rat   592 -------SSNIVSG----TTTKITTIPMTSKP---NVIVVQK----TTGKG-----------TTI 627

  Fly   757 SGLTSSAKQPGLGNKPTTLTFATAGGGKNNLVFLPASAASGMRALTLATKPKSNVLV-----IGA 816
            .||      || .|..|||..|   ||:..|..:|..|..   |:..||:|.:.::|     ||:
  Rat   628 QGL------PG-KNVVTTLLNA---GGEKTLQTVPTGAKP---AIITATRPITKMIVTQPKGIGS 679

  Fly   817 STSPASAASSP-----NPSGGT----KPK------------ANQLITEDTPIDIINMPIIVADNG 860
            :..|| |...|     ...|.|    |||            ..||:||     .:.....||:.|
  Rat   680 TVQPA-AKIIPTKIVYGQQGKTQVLIKPKPVTFQATVVSEQTRQLVTE-----TLQQASRVAEAG 738

  Fly   861 -------------------TAAELNQASVKNSPLVVFNAT---DW---EMELDQAAT---KSAST 897
                               ::.|.:|:|..:.|:|...|:   ||   |:.::.:.|   :..|:
  Rat   739 NSSAQEGKEEPQGYTDSSSSSTESSQSSQDSQPVVHVIASRRQDWSEHEIAMETSPTIIYQDVSS 803

  Fly   898 TSKQALDDV--IIEEDEDAEEEARESSEQPSTMDLNNSIIEL-------HPEDDSAIEYVDMDLE 953
            .|:.|...:  ::|..:...:|..||..:..|:||:...:.:       |..:..:|..|:.:|
  Rat   804 ESQSATSTIKALLELQQTTVKEKLESKPRQPTIDLSQMAVPIQMTQEKRHSPESPSIAVVESEL- 867

  Fly   954 QPVEIESTSNISPETATTTLKAAIVSTSPQQQQQQPQKKHPPLEHPLSAGAAAGTGSSTGAAVQS 1018
              |....|:..:.|.........:...|..||..|||:  ..|:|.    |.:.|.:.|...|:|
  Rat   868 --VAEYITTERTDEGTEVAFPLLVSHRSQPQQPSQPQR--TLLQHV----AQSQTATQTSVVVKS 924

  Fly  1019  1018
              Rat   925  924

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15356	NP_608633.1	ENT	16..82	CDD:281696	37/79 (47%)
Emsy	XP_006229864.1	ENT	19..81	CDD:281696	36/61 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342684
Domainoid	1	1.000	72	1.000	Domainoid score	I9164
eggNOG	1	0.900	-	-		E1_KOG4675
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	153	1.000	Inparanoid score	I4257
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008212
OrthoInspector	1	1.000	-	-		oto95933
orthoMCL	1	0.900	-	-		OOG6_109408
Panther	1	1.100	-	-	LDO	PTHR16500
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.840