DRSC/TRiP Functional Genomics Resources

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Protein Alignment DNAJB1 and Droj2

DIOPT Version :10

Sequence 1:NP_006136.1 Gene:DNAJB1 / 3337 HGNCID:5270 Length:340 Species:Homo sapiens
Sequence 2:NP_650283.1 Gene:Droj2 / 41646 FlyBaseID:FBgn0038145 Length:403 Species:Drosophila melanogaster


Alignment Length:401 Identity:127/401 - (31%)
Similarity:186/401 - (46%) Gaps:122/401 - (30%)


- Green bases have known domain annotations that are detailed below.


Human     5 YYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGE 69
            ||..||:...|:.:|:|:|||:.||:||||||  |...||||.|::||:||||..||:::|..||
  Fly     7 YYDILGVKPNATPDELKKAYRKLALKYHPDKN--PNEGEKFKAISQAYEVLSDADKRQVYDEGGE 69

Human    70 EGLKGSGPSGGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNP---FDTFFGQRNGEEGMDIDDPF 131
            ..:|        .|||:...|                  |||   |:.|||              
  Fly    70 AAIK--------KGGADSGDF------------------RNPMDFFEKFFG-------------- 94

Human   132 SGFPMGMGGFTNVNFGRSRSAQEPARKKQDPPVTHDLRVSLEEIYSGCTKKMKISH--------- 187
            :||. |.||      ||.|.     |:.:|  |.|.:.|.|||:|:|.|:|:::..         
  Fly    95 AGFG-GSGG------GRRRE-----RRGKD--VVHQMSVQLEELYNGATRKLQLQKNVICDKCEG 145

Human   188 --------------------------------------KRLNPDGKSIRNED------------- 201
                                                  ::.:..|::|:.:|             
  Fly   146 RGGKKGSIEKCLQCRGNGVETRVQQIAPGIMQHIEQVCRKCSGTGETIQEKDRCKNCSGRKTVRE 210

Human   202 -KILTIEVKKGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREA 265
             |:|.:.::||.::|.||.|..|||....:.|.||:.:|.:|.|:.|...|.|::....:.|.||
  Fly   211 RKVLEVHIEKGMRDGQKIVFTGEGDHEPESQPGDIIILLDEKEHSTFAHAGQDLMMKMPLQLVEA 275

Human   266 LCGCTVNVPTLDGRTIPVVFK--DVIRPGMRRKVPGEGLPLPKTPEKRGDLIIEFEVIFPERIPQ 328
            |||....|.|||.|.:.|..:  :|||..|.:.:..||:|:.|.|.::|.|||:|||||||.|..
  Fly   276 LCGFQRIVKTLDDRDLIVSTQPGEVIRHEMTKCIAEEGMPIFKNPMEKGTLIIQFEVIFPEVINP 340

Human   329 TSRTVLEQVLP 339
            :....|:|.||
  Fly   341 SVVPTLKQCLP 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DNAJB1NP_006136.1 DnaJ_bact 4..336 CDD:274090 124/396 (31%)
Droj2NP_650283.1 PTZ00037 2..398 CDD:240236 127/401 (32%)

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