Protein Alignment DNAJB1 and DnaJ-1

DIOPT Version :10

• Sequence 1: NP_006136.1
• Gene: DNAJB1 / 3337
• HGNCID: 5270
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_523936.2
• Gene: DnaJ-1 / 38643
• FlyBaseID: FBgn0263106
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 348
• Identity: 187/348 - (53%)
• Similarity: 241/348 - (69%)
• Gaps: 24/348 - (6%)

Human     1 MGKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFD 65
            ||||:|:.|||.|.|||:|||:|||:.||:|||||||.|.|||:||||||||:||||.:||:|||
  Fly     1 MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFD 65

Human    66 RYGEEGLKGSGPSGGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGMDIDDP 130
            .|||:||||..| |..|||..| :::|.|||||.|.||:|||..:||..||   .|.:.|
  Fly    66 NYGEDGLKGGQP-GPDGGGQPG-AYTYQFHGDPRATFAQFFGSSDPFGAFF---TGGDNM----- 120

Human   131 FSGFPMGMGGFTNVNFGR-------SRSAQEPARKK-QDPPVTHDLRVSLEEIYSGCTKKMKISH 187
            |||   |.||.||..|..       :.:||.|:||: ||||:.|||.|||||:..||.||||||.
  Fly   121 FSG---GQGGNTNEIFWNIGGDDMFAFNAQAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKMKISR 182

Human   188 KRLNPDGKSIRNEDKILTIEVKKGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGS 252
            .....:|.  ..|:|:|.|.||.|||.|||||||:|||...|..||||||:::||||::|||:|.
  Fly   183 MATGSNGP--YKEEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFIIRDKPHSLFKREGI 245

Human   253 DVIYPARISLREALCGCTVNVPTLDGRTIPV-VFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLII 316
            |:.|.|:|||::||||..|:||||.|..|.| ...::|:|...|::.|.|||:||.|.:|||||:
  Fly   246 DLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLPVPKEPSRRGDLIV 310

Human   317 EFEVIFPERIPQTSRTVLEQVLP 339
            .|::.||:.:..:.:..|.::||
  Fly   311 SFDIKFPDTLAPSLQNQLSELLP 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB1	NP_006136.1	DnaJ_bact	4..336	CDD:274090	182/340 (54%)
DnaJ-1	NP_523936.2	DnaJ_bact	4..332	CDD:274090	182/342 (53%)