Protein Alignment DNAJB1 and CG5001

DIOPT Version :9

• Sequence 1: NP_006136.1
• Gene: DNAJB1 / 3337
• HGNCID: 5270
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_001245832.1
• Gene: CG5001 / 33308
• FlyBaseID: FBgn0031322
• Length: 350
• Species: Drosophila melanogaster
• Alignment Length: 355
• Identity: 179/355 - (50%)
• Similarity: 241/355 - (67%)
• Gaps: 22/355 - (6%)

Human     1 MGKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFD 65
            ||||||:.|||.:.|:|:|||:|||:.||||||||||...||:||||:||||:||||..|||::|
  Fly     1 MGKDYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYD 65

Human    66 RYGEEGLKGSGPSGGS-GGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNG---EEGMD 126
            :|||:|||    |||: .||.:..||:|.|||||.|.||:|||..|||.:||...:.   ::..|
  Fly    66 KYGEDGLK----SGGTRNGGPSSNSFTYQFHGDPRATFAQFFGNSNPFASFFDMGDNLFDKKVFD 126

Human   127 ID-------DPFSGFPM--GMG-GFTNVNFGRSRSAQEPARK--KQDPPVTHDLRVSLEEIYSGC 179
            :|       .||.|...  |:| ||.......|.:...|.:|  ||||||.|||.|:|||||.||
  Fly   127 LDTEPDFFSSPFGGIGSRHGLGSGFRPSFRSHSFNVHTPFKKEQKQDPPVEHDLYVTLEEIYHGC 191

Human   180 TKKMKISHKRLNPDGKSIRNEDKILTIEVKKGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPH 244
            .||||||.:.:..||.| |.|:|.|.|.:|.|||.|||:||.|||||....|||||||:::||||
  Fly   192 VKKMKISRRIVQADGSS-RKEEKFLAISIKPGWKSGTKVTFQKEGDQAPGKIPADIVFIIRDKPH 255

Human   245 NIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPV-VFKDVIRPGMRRKVPGEGLPLPKTP 308
            .:|||:|||:.|.||::|::||||....|||:.|..:.: ..:::|:|...:::.|.|||.||..
  Fly   256 AMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRISTMQEIIKPNTVKRIQGYGLPFPKDT 320

Human   309 EKRGDLIIEFEVIFPERIPQTSRTVLEQVL 338
            .::|||::.|::.|||::....:.||:.:|
  Fly   321 TRKGDLLVAFDIQFPEKLTAAQKEVLKDML 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB1	NP_006136.1	DnaJ	1..340	CDD:223560	179/355 (50%)
CG5001	NP_001245832.1	DnaJ	1..347	CDD:223560	177/350 (51%)
		DnaJ	4..65	CDD:278647	41/60 (68%)
		DnaJ_C	174..338	CDD:199909	86/164 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165154071
Domainoid	1	1.000	190	1.000	Domainoid score	I3265
eggNOG	1	0.900	-	-		E2759_KOG0714
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	371	1.000	Inparanoid score	I2129
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53515
OrthoDB	1	1.010	-	-		D1393097at2759
OrthoFinder	1	1.000	-	-		FOG0000274
OrthoInspector	1	1.000	-	-		mtm8440
orthoMCL	1	0.900	-	-		OOG6_100302
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1020
SonicParanoid	1	1.000	-	-		X227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.700