Protein Alignment DNAJB1 and shv

DIOPT Version :10

• Sequence 1: NP_006136.1
• Gene: DNAJB1 / 3337
• HGNCID: 5270
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_608525.1
• Gene: shv / 33220
• FlyBaseID: FBgn0031256
• Length: 354
• Species: Drosophila melanogaster
• Alignment Length: 378
• Identity: 111/378 - (29%)
• Similarity: 172/378 - (45%)
• Gaps: 99/378 - (26%)

Human     2 GKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNK-EPGAEEKFKEIAEAYDVLSDPRKREIFD 65
            |:|:|:.|.:.:.|:..|:|:||||.|...|||||| :|.|..||:::..||:|||:|.||:.:|
  Fly    23 GRDFYKILNVKKNANTNEVKKAYRRLAKELHPDKNKDDPDASTKFQDLGAAYEVLSNPDKRKTYD 87

Human    66 RYGEEGLKGSGPSGGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGMDIDDP 130
            |.|||.||..|.....|                           :||.:|||.
  Fly    88 RCGEECLKKEGMMDHGG---------------------------DPFSSFFGD------------ 113

Human   131 FSGFPMGMGGFTNVNFGRSRSAQEPARKKQDPP----VTHDLRVSLEEIYSG------------- 178
             .||..|..|                 ::||.|    :..||.|||||:|||
  Fly   114 -FGFHFGGDG-----------------QQQDAPRGADIVMDLYVSLEELYSGNFVEIVRNKPVTK 160

Human   179 -------CTKKMKISHKRLNPDGK---------------SIRNEDKILTIEVKKGWKEGTKITFP 221
                   |..:.::..:.|.| |:               .:.||::.|.|||::|..:|.:..|.
  Fly   161 PASGTRKCNCRQEMVTRNLGP-GRFQMIQQTVCDECPNVKLVNEERTLEIEVEQGMVDGQETRFV 224

Human   222 KEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFK 286
            .||:...:..|.|::..::..||..|.|...|:.....|||::||.|.::.:..|||..:||..:
  Fly   225 AEGEPHIDGEPGDLIVRVQQMPHPRFLRKNDDLYTNVTISLQDALVGFSMEIKHLDGHLVPVTRE 289

Human   287 DVIRPGMRRKVPGEGLPLPKTPEKRGDLIIEFEVIFPER-IPQTSRTVLEQVL 338
            .|..||.|.:..|||:|..:.....|:|.|.|:|.||:: :.:..:..|:::|
  Fly   290 KVTWPGARIRKKGEGMPNFENNNLTGNLYITFDVEFPKKDLTEEDKEALKKIL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DNAJB1	NP_006136.1	DnaJ_bact	4..336	CDD:274090	109/372 (29%)
shv	NP_608525.1	DnaJ_bact	25..345	CDD:274090	110/376 (29%)