DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Der-1 and DER1

DIOPT Version :9

Sequence 1:	NP_001259892.1	Gene:	Der-1 / 33369	FlyBaseID:	FBgn0267972	Length:	245	Species:	Drosophila melanogaster
Sequence 2:	NP_194662.2	Gene:	DER1 / 829054	AraportID:	AT4G29330	Length:	266	Species:	Arabidopsis thaliana

Alignment Length:	272	Identity:	77/272 - (28%)
Similarity:	120/272 - (44%)	Gaps:	45/272 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 GVWYRSLPRFTRYWLTATVVLSMLCRFD--------VIPLHWLHLDRSAVFSKLQLWRCMTSLFV 60
            |.:|.|||..|:.:.|       ||.|.        |.|:| :.|....|..:.|:||.:|:||.
plant     5 GEFYNSLPPITKAYGT-------LCFFTTVATQLGLVAPVH-IALIPELVLKQFQIWRLITNLFF 61

  Fly    61 FPISSNTAFHFLINCFFIVQYSSKLEKDQYSRSPADYLYLLIVSAVLANIGGMI--FNVYFLMDT 123
            .   ...:.:|.|....|.:|..:|||..:.|..||:|:::|..:....:..:|  |...||..:
plant    62 L---GGFSINFGIRLLMIARYGVQLEKGPFERRTADFLWMMIFGSFTLLVLSVIPFFWTPFLGVS 123

  Fly   124 LVLAITYIWCQLNKDVTVSFWFGTRFKAMYLPWVLAAFEFIFHFS-LASLVGIFVGHVYYFFKFQ 187
            ||..:.|:|.:...:..:|.:.....||.||||.:.|.:.||... :..|:||..||:|||....
plant   124 LVFMLLYLWSREFPNANISLYGLVTLKAFYLPWAMLALDVIFGSPIMPDLLGIIAGHLYYFLTVL 188

  Fly   188 YSQDLGGTPLLETPQFLKRLV----------------------PDVSGGFGGFGLPPESRAPPRQ 230
            :....|.. .|:||:::.::|                      |...||.||.|....:||||..
plant   189 HPLATGKN-YLKTPKWVNKIVARWRIGAPVASVRQAGGVGAAGPGAGGGVGGGGAYSSARAPPES 252

  Fly   231 ATESPWGRGMTL 242
            :..:..||...|
plant   253 SNTAFRGRSYRL 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Der-1	NP_001259892.1	DER1	10..202	CDD:282380	59/202 (29%)
DER1	NP_194662.2	Rhomboid	11..201	CDD:419717	58/201 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5291
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54051
OrthoDB	1	1.010	-	-		D1609512at2759
OrthoFinder	1	1.000	-	-		FOG0000789
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11009
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.890