Protein Alignment Der-1 and DERL2

DIOPT Version :9

• Sequence 1: NP_001259892.1
• Gene: Der-1 / 33369
• FlyBaseID: FBgn0267972
• Length: 245
• Species: Drosophila melanogaster
• Sequence 2: NP_057125.2
• Gene: DERL2 / 51009
• HGNCID: 17943
• Length: 239
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 69/249 - (27%)
• Similarity: 118/249 - (47%)
• Gaps: 32/249 - (12%)

  Fly     7 YRSLPRFTRYWLTATVVLSMLCRFDVIPLHWLHLDRSAVFSKLQLWRCMTS-LFVFPISSNTAFH 70
            |..:|..:|.:.||.|:.:...:.::|....|:.:...:|...|:||.:|: ||..|:    .|:
Human    10 YLQIPPVSRAYTTACVLTTAAVQLELITPFQLYFNPELIFKHFQIWRLITNFLFFGPV----GFN 70

  Fly    71 FLINCFFIVQYSSKLEKDQYSRSPADYLYLLIVSAVLANIGGMIFNVYFLMDTLVLAITYIWCQL 135
            ||.|..|:.:|...||:..:....||::::.:....|..:.|:..::.||.....:.:.|:|.:.
Human    71 FLFNMIFLYRYCRMLEEGSFRGRTADFVFMFLFGGFLMTLFGLFVSLVFLGQAFTIMLVYVWSRR 135

  Fly   136 NKDVTVSFWFGTRFKAMYLPWVLAAFEFIFHFS-LASLVGIFVGHVYYFFKFQYSQDLGGTPLLE 199
            |..|.::|:....|:|.:|||||..|..:...| :..|:||.|||:|:|.:..:....||..:|:
Human   136 NPYVRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRILK 200

  Fly   200 TPQFLKRL--VPDVSGGF--------GGFGLPPESRAPPRQATESPWGRGMTLG 243
            ||..||.:  .||....:        |||.                ||.|..||
Human   201 TPSILKAIFDTPDEDPNYNPLPEERPGGFA----------------WGEGQRLG 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Der-1	NP_001259892.1	DER1	10..202	CDD:282380	55/193 (28%)
DERL2	NP_057125.2	DER1	13..203	CDD:398288	55/193 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..239		8/40 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5291
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54051
OrthoDB	1	1.010	-	-		D1609512at2759
OrthoFinder	1	1.000	-	-		FOG0000789
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2482
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.860