DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Wdr62 and Wdr38

DIOPT Version :9

Sequence 1:NP_001259886.1 Gene:Wdr62 / 33367 FlyBaseID:FBgn0031374 Length:2397 Species:Drosophila melanogaster
Sequence 2:NP_083963.1 Gene:Wdr38 / 76646 MGIID:1923896 Length:303 Species:Mus musculus


Alignment Length:306 Identity:73/306 - (23%)
Similarity:125/306 - (40%) Gaps:42/306 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   497 YDGRNG-VRCIKISPELQHL--ASGDRCGNIRVYSLVNLRLLTTIEAHESEVLCLEYSNEKIERK 558
            |...:| |.|...||:.:.|  ||.|.|  :.|:...:.|||..:..|...|....:|.   :.:
Mouse    22 YGQHHGEVNCSAFSPDGRTLLTASDDGC--VYVWGTKSGRLLWRLAGHRGPVKSCCFSP---DGR 81

  Fly   559 LLASASRDRLIHVFDVAQNYLLLQTLDDHSSSITSIKFVGAGLNFQMISCGADKSIMFRSFQGNI 623
            |:||:|.|..|.::|||:: ..|..|..|..|:.::.|  :..:.|:.|.|.||..:....|   
Mouse    82 LIASSSSDHSIRLWDVARS-KCLHVLKGHQRSVETVSF--SPDSKQLASGGWDKRAIVWEVQ--- 140

  Fly   624 FMRGTNTSGK---------TTLYDMEVDSNAKHILTACQDRNVRVYGTQNAKQTKTFKGSHSDEG 679
                   ||:         .::...:....:..:.|...|..|.::..:.:....::.......|
Mouse   141 -------SGRRVHLLVGHCDSIQSSDFSPTSDSLATGSWDSTVHIWDLRASTPVVSYHNLEGHTG 198

  Fly   680 SLIKLSLDPSGIYVATSCTDKTLAVYDYYSNECMARMYGHSELVTGLKFTNDCRHLISASGDGCI 744
            ::..|....||: :|:...|||:.|:...:|....::.||:..|..|.|:.|...|.||.....:
Mouse   199 NISCLCYSASGL-LASGSWDKTICVWKPTTNNLPLQLKGHTIWVNSLAFSPDELKLASAGYSRTV 262

  Fly   745 FIWQVPHDMIVTMQARMSQQRLRSGHAPLPRPLAPISPPDGIVLES 790
            .:|    |.:........:..|...|       |.|..|||.:|.|
Mouse   263 KVW----DCLTGKCLETLKGMLDVAH-------ACIFTPDGKLLVS 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wdr62NP_001259886.1 WD40 73..448 CDD:295369
WD40 repeat 73..107 CDD:293791
WD40 repeat 113..161 CDD:293791
WD40 158..574 CDD:225201 24/79 (30%)
WD40 repeat 167..207 CDD:293791
WD40 repeat 209..285 CDD:293791
WD40 repeat 254..294 CDD:293791
WD40 repeat 303..338 CDD:293791
WD40 repeat 353..407 CDD:293791
WD40 385..747 CDD:225201 62/261 (24%)
WD40 436..748 CDD:295369 62/262 (24%)
WD40 repeat 505..540 CDD:293791 12/36 (33%)
WD40 repeat 546..586 CDD:293791 12/39 (31%)
WD40 repeat 591..631 CDD:293791 7/39 (18%)
WD40 repeat 637..672 CDD:293791 3/34 (9%)
WD40 repeat 679..717 CDD:293791 10/37 (27%)
WD40 repeat 723..749 CDD:293791 8/25 (32%)
Wdr38NP_083963.1 WD40 <18..300 CDD:225201 73/306 (24%)
WD 1 24..63 14/40 (35%)
WD40 25..300 CDD:238121 72/303 (24%)
WD40 repeat 31..66 CDD:293791 12/36 (33%)
WD 2 66..105 13/42 (31%)
WD40 repeat 72..108 CDD:293791 12/39 (31%)
WD 3 108..147 11/50 (22%)
WD40 repeat 113..149 CDD:293791 9/47 (19%)
WD 4 150..189 3/38 (8%)
WD40 repeat 156..194 CDD:293791 3/37 (8%)
WD 5 195..233 10/38 (26%)
WD40 repeat 200..235 CDD:293791 9/35 (26%)
WD 6 236..277 11/44 (25%)
WD 7 279..303 9/26 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833460
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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