DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wdr62 and WDR38

DIOPT Version :9

Sequence 1:NP_001259886.1 Gene:Wdr62 / 33367 FlyBaseID:FBgn0031374 Length:2397 Species:Drosophila melanogaster
Sequence 2:NP_001263303.1 Gene:WDR38 / 401551 HGNCID:23745 Length:315 Species:Homo sapiens


Alignment Length:307 Identity:67/307 - (21%)
Similarity:127/307 - (41%) Gaps:26/307 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly   499 GRNG--VRCIKISPELQHLASGDRCGNIRVYSLVNLRLLTTIEAHESEVLCLEYSNEKIERKLLA 561
            |::|  |.....||:.|.|.:|...|.:..:...:.:||..:..|...|....:|.   :..|.|
Human    18 GQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSP---DGHLFA 79

  Fly   562 SASRDRLIHVFDVAQNYLLLQTLDDHSSSITSIKFVGAGLNFQMISCGADKSIMFRSFQGNIFMR 626
            |||.|..:.::|||: ...|:.|..|..|:.::.|  :..:.|:.|.|.||.:|....|....:|
Human    80 SASCDCTVRLWDVAR-AKCLRVLKGHQRSVETVSF--SPDSRQLASGGWDKRVMLWDVQSGQMLR 141

  Fly   627 ---GTNTSGKTTLYDMEVDSNAKHILTACQDRNVRVYGTQNAKQTKTFKGSHSDEGSLIKLSLDP 688
               |...|.:::.:...|:.    :.|...|..|.::..:......:.:.......::..|....
Human   142 LLVGHRDSIQSSDFSPTVNC----LATGSWDSTVHIWDLRMVTPAVSHQALEGHSANISCLCYSA 202

  Fly   689 SGIYVATSCTDKTLAVYDYYSNECMARMYGHSELVTGLKFTNDCRHLISASGDGCIFIWQVPHDM 753
            ||: :|:...|||:.::...::..:.::.||...|..:.|:.|...|.||.....:.:|.     
Human   203 SGL-LASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGYSRMVKVWD----- 261

  Fly   754 IVTMQARMSQQRLRSGHAPLPRPLAPISPPDGIVLESPTSEIEQPQL 800
               .......:.|:.|...:....|  ..|||.:|.|..::..:.|:
Human   262 ---CNTGKCLETLKQGVLDVAHTCA--FTPDGKILVSGAADQTRRQI 303

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wdr62NP_001259886.1 WD40 73..448 CDD:295369
WD40 repeat 73..107 CDD:293791
WD40 repeat 113..161 CDD:293791
WD40 158..574 CDD:225201 20/76 (26%)
WD40 repeat 167..207 CDD:293791
WD40 repeat 209..285 CDD:293791
WD40 repeat 254..294 CDD:293791
WD40 repeat 303..338 CDD:293791
WD40 repeat 353..407 CDD:293791
WD40 385..747 CDD:225201 57/252 (23%)
WD40 436..748 CDD:295369 57/253 (23%)
WD40 repeat 505..540 CDD:293791 8/34 (24%)
WD40 repeat 546..586 CDD:293791 12/39 (31%)
WD40 repeat 591..631 CDD:293791 10/42 (24%)
WD40 repeat 637..672 CDD:293791 4/34 (12%)
WD40 repeat 679..717 CDD:293791 7/37 (19%)
WD40 repeat 723..749 CDD:293791 7/25 (28%)
WDR38NP_001263303.1 WD40 <11..299 CDD:225201 66/301 (22%)
WD 1 19..58 10/38 (26%)
WD40 20..301 CDD:238121 65/301 (22%)
WD40 repeat 26..61 CDD:293791 8/34 (24%)
WD 2 61..100 13/42 (31%)
WD40 repeat 67..103 CDD:293791 12/39 (31%)
WD 3 103..142 10/40 (25%)
WD40 repeat 108..144 CDD:293791 9/37 (24%)
WD 4 145..184 6/42 (14%)
WD40 repeat 151..189 CDD:293791 4/41 (10%)
WD 5 190..228 7/38 (18%)
WD40 repeat 195..230 CDD:293791 7/35 (20%)
WD 6 231..272 9/48 (19%)
WD40 repeat 236..272 CDD:293791 7/43 (16%)
WD 7 275..313 7/31 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 295..315 1/9 (11%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165143283
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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