DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wdr62 and Lis-1

DIOPT Version :9

Sequence 1:NP_001259886.1 Gene:Wdr62 / 33367 FlyBaseID:FBgn0031374 Length:2397 Species:Drosophila melanogaster
Sequence 2:NP_001246361.1 Gene:Lis-1 / 36791 FlyBaseID:FBgn0015754 Length:411 Species:Drosophila melanogaster


Alignment Length:269 Identity:63/269 - (23%)
Similarity:113/269 - (42%) Gaps:27/269 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly   500 RNGVRCIKISPELQHLASGDRCGNIRVYSLVNLRLLTTIEAHESEVLCLEYSNEKIERKLLASAS 564
            |..:..:...|....:.|......||::.........:::.|...|..:.:.   .:.|||||.|
  Fly   108 RASITRVIFHPIFALMVSASEDATIRIWDFETGEYERSLKGHTDSVQDVAFD---AQGKLLASCS 169

  Fly   565 RDRLIHVFDVAQNYLLLQTLDDHSSSITSIKFVGAGLNFQMISCGADKSI-MFRSFQGNIFMRGT 628
            .|..|.::|..|:|..::|:..|..:::|:.||.||  ..::|...|::| |:....|  :...|
  Fly   170 ADLSIKLWDFQQSYECIKTMHGHDHNVSSVAFVPAG--DYVLSASRDRTIKMWEVATG--YCVKT 230

  Fly   629 NTSGKTTLYDMEVDSNAKHILTACQDRNVRVYGTQNAKQTKTFKGSHSDEGSLIKLSLDPS---- 689
            .|..:..:..:.|........|...|:.:||:.| |:|..|.....|......|..:.:.:    
  Fly   231 YTGHREWVRMVRVHIEGSIFATCSNDQTIRVWLT-NSKDCKVELRDHEHTVECIAWAPEAAASAI 294

  Fly   690 --------------GIYVATSCTDKTLAVYDYYSNECMARMYGHSELVTGLKFTNDCRHLISASG 740
                          |.::|:...|||:.::|.....|:..:.||...|.||.|....::|:|||.
  Fly   295 NEAAGADNKKGHHQGPFLASGSRDKTIRIWDVSVGLCLLTLSGHDNWVRGLAFHPGGKYLVSASD 359

  Fly   741 DGCIFIWQV 749
            |..|.:|.:
  Fly   360 DKTIRVWDL 368

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wdr62NP_001259886.1 WD40 73..448 CDD:295369
WD40 repeat 73..107 CDD:293791
WD40 repeat 113..161 CDD:293791
WD40 158..574 CDD:225201 15/73 (21%)
WD40 repeat 167..207 CDD:293791
WD40 repeat 209..285 CDD:293791
WD40 repeat 254..294 CDD:293791
WD40 repeat 303..338 CDD:293791
WD40 repeat 353..407 CDD:293791
WD40 385..747 CDD:225201 62/265 (23%)
WD40 436..748 CDD:295369 62/266 (23%)
WD40 repeat 505..540 CDD:293791 4/34 (12%)
WD40 repeat 546..586 CDD:293791 12/39 (31%)
WD40 repeat 591..631 CDD:293791 11/40 (28%)
WD40 repeat 637..672 CDD:293791 9/34 (26%)
WD40 repeat 679..717 CDD:293791 8/55 (15%)
WD40 repeat 723..749 CDD:293791 11/25 (44%)
Lis-1NP_001246361.1 LisH 9..40 CDD:128913
WD40 100..409 CDD:238121 63/269 (23%)
WD40 repeat 111..148 CDD:293791 4/36 (11%)
WD40 repeat 154..191 CDD:293791 12/39 (31%)
WD40 repeat 196..232 CDD:293791 11/39 (28%)
WD40 repeat 239..274 CDD:293791 9/35 (26%)
WD40 repeat 280..336 CDD:293791 8/55 (15%)
WD40 repeat 342..378 CDD:293791 11/27 (41%)
WD40 repeat 384..408 CDD:293791
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45442358
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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