DRSC/TRiP Functional Genomics Resources

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Protein Alignment Wdr62 and Dcaf4

DIOPT Version :9

Sequence 1:NP_001259886.1 Gene:Wdr62 / 33367 FlyBaseID:FBgn0031374 Length:2397 Species:Drosophila melanogaster
Sequence 2:XP_006240409.1 Gene:Dcaf4 / 362762 RGDID:1306241 Length:519 Species:Rattus norvegicus


Alignment Length:541 Identity:98/541 - (18%)
Similarity:171/541 - (31%) Gaps:197/541 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   326 FNSATLEYVTTLPRTHYLGVDVAQGIQINHIMSVPQQAKFPDCIAMVFDEQRSKVSCV-YNDHSL 389
            |:.....|...||..:.......:|||:..:.|...|      :....|:|:.|::.| :|..|:
  Rat    70 FDPEKNRYFRLLPGHNNCNPLTKEGIQLKEMESRRLQ------LLQQEDKQKKKIARVGFNASSI 128

  Fly   390 YIWDLRDISRVGKSHSFL-YHSTCIWGVETVPYNVEREPSQTLPEECFVTCSSDDTIRVWGLDGC 453
                ||. :::|    || :.|.|                 .|..|..|.|.....:.:...|  
  Rat   129 ----LRK-NQLG----FLNFSSYC-----------------RLSHELRVACMERKKVEIQSSD-- 165

  Fly   454 TNNDIYRRNIYSKELLKIVYSD---DELQFIKDQGSSLFDKAGNSSYDGRNGVRCIKISPELQHL 515
                   .:..:.:....:.:|   |.|..:.|.      |.|.|.|.                 
  Rat   166 -------PSALASDRFNFILADTTSDRLFTVNDV------KIGGSKYG----------------- 200

  Fly   516 ASGDRCGNIRVYSLVNLRLLTTIEAHESEVLCLEYSNEKIERKLLASASRDRLIHVFDVAQNYLL 580
                      :.||..|: ..|.|.|..|  .|.::|.|:.....||     |.|:    .:::|
  Rat   201 ----------IISLQGLK-APTFEVHMHE--NLYFTNRKVNSVCWAS-----LNHL----DSHIL 243

  Fly   581 L------------------------QTLDDHSSSITSIKFVGA-----GLNFQMISC---GADKS 613
            |                        |...|....:.|.:..||     .||.|..:|   |..:.
  Rat   244 LCLMGLAETPGCATLLPASLFVSSHQAGTDQPGMLCSFRIPGAWSCAWSLNVQANNCFSTGLSRR 308

  Fly   614 IMF--------RSFQGNIFMRGTNTSGKTTLYDMEVDSNAKHILTACQDRNVRVYGTQNAKQTKT 670
            ::.        :|:..|..:.....:.||.|           :...|:...:.....::..|.|.
  Rat   309 VLLTNVVTGHRQSYWTNSDVLAQQFAVKTPL-----------LFNGCRSGEIFAIDLRSPSQAKG 362

  Fly   671 FKGS---HSDEGSLIKLSLDPSGIYVATSCTDKTLAVYDYYSNECMARMYGHSELVTGLKFTNDC 732
            :|.:   |....:.:::..:..  |:..|.....:.::|..:.:|:.:..||         .|:.
  Rat   363 WKATQIFHDSAVTSVQVFKEEQ--YLMASDMAGKIKLWDLRATKCVRQYEGH---------VNEY 416

  Fly   733 RHL----------ISASGDGCIF-IWQVPHDMIVTMQARMSQQRLRSGHAPLPRPLAPISPPDGI 786
            .:|          :.|.|..|.. ||.: ||      ||:    ||:    :|.|          
  Rat   417 AYLPLHMHEEEGILVAVGQDCYTRIWSL-HD------ARL----LRT----IPSP---------- 456

  Fly   787 VLESPTSEIEQPQL--QPKFG 805
               .|||:...|.:  .|:.|
  Rat   457 ---CPTSKANIPSVAFSPRLG 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Wdr62NP_001259886.1 WD40 73..448 CDD:295369 26/123 (21%)
WD40 repeat 73..107 CDD:293791
WD40 repeat 113..161 CDD:293791
WD40 158..574 CDD:225201 49/252 (19%)
WD40 repeat 167..207 CDD:293791
WD40 repeat 209..285 CDD:293791
WD40 repeat 254..294 CDD:293791
WD40 repeat 303..338 CDD:293791 2/11 (18%)
WD40 repeat 353..407 CDD:293791 11/54 (20%)
WD40 385..747 CDD:225201 69/419 (16%)
WD40 436..748 CDD:295369 59/368 (16%)
WD40 repeat 505..540 CDD:293791 4/34 (12%)
WD40 repeat 546..586 CDD:293791 10/63 (16%)
WD40 repeat 591..631 CDD:293791 10/55 (18%)
WD40 repeat 637..672 CDD:293791 3/34 (9%)
WD40 repeat 679..717 CDD:293791 4/37 (11%)
WD40 repeat 723..749 CDD:293791 7/36 (19%)
Dcaf4XP_006240409.1 WD40 repeat 286..324 CDD:293791 7/37 (19%)
WD40 <302..471 CDD:225201 36/218 (17%)
WD40 <314..471 CDD:295369 35/206 (17%)
WD40 repeat 329..368 CDD:293791 7/49 (14%)
WD40 repeat 374..410 CDD:293791 4/37 (11%)
WD40 repeat 418..454 CDD:293791 12/50 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166337025
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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