DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15358 and CLEC4A

DIOPT Version :9

Sequence 1:	NP_001303306.2	Gene:	CG15358 / 33366	FlyBaseID:	FBgn0031373	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_057268.1	Gene:	CLEC4A / 50856	HGNCID:	13257	Length:	237	Species:	Homo sapiens

Alignment Length:	103	Identity:	23/103 - (22%)
Similarity:	48/103 - (46%)	Gaps:	5/103 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 PK-FELIGSRFFYIEDETRRNWTSAGSACRQMGTQLATIRSAEELAALRAKLNKERHYWLDITDL 189
            || ::...|..::|..|: .:|..:...|.:|...|..|.:.||...:...|.:|..|::.::|.
Human   107 PKNWKSFSSNCYFISTES-ASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDP 170

  Fly   190 EKEGDFR-ISASGKRPNFLKWRAGQPNNFSGNQHCVDL 226
            |.:..:: :..:....:...|...:|::  .|:.||.|
Human   171 EGQRHWQWVDQTPYNESSTFWHPREPSD--PNERCVVL 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15358	NP_001303306.2	CLECT	141..245	CDD:153057	19/87 (22%)
CLEC4A	NP_057268.1	ITIM motif. /evidence=ECO:0000269\|PubMed:20530286	5..10
		CLECT_DC-SIGN_like	106..232	CDD:153060	23/103 (22%)
		Mannose binding. /evidence=ECO:0000269\|PubMed:27015765, ECO:0007744\|PDB:5B1X	195..197		0/1 (0%)
		N-acetyl-D-glucosamine binding. /evidence=ECO:0000269\|PubMed:27015765, ECO:0007744\|PDB:5B1X	207..209		23/103 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010