DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15358 and ASGR1

DIOPT Version :9

Sequence 1:	NP_001303306.2	Gene:	CG15358 / 33366	FlyBaseID:	FBgn0031373	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001662.1	Gene:	ASGR1 / 432	HGNCID:	742	Length:	291	Species:	Homo sapiens

Alignment Length:	218	Identity:	46/218 - (21%)
Similarity:	80/218 - (36%)	Gaps:	54/218 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 ATEARL-----------ARIETLQTAMNIRQKVLQEGFP------KDIVARLDRLESQQAALLRI 115
            :|||::           .::::|::.:..:||.|.|...      |..|:.|..|..|.|||
Human    83 STEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAAL--- 144

  Fly   116 LSKFDRKIVAPKFELIGSRFFYIEDETRRNWTSAGSACRQMGTQLATIRSAEELAALRAKLNKER 180
            ......:...|...:...|..|....:.:.|..|.:.||.....|..:.|.||...::..:....
Human   145 QGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVN 209

  Fly   181 HY-----------WLDITDLEKEGDFRISASGKRPNFLKWRAGQPNNFSGN--------QHCVDL 226
            .:           |:|.||.|             ..|..||..||:::.|:        .|..|
Human   210 TWMGLHDQNGPWKWVDGTDYE-------------TGFKNWRPEQPDDWYGHGLGGGEDCAHFTD- 260

  Fly   227 LDGLMYDNKCESLSYFICQSDDD 249
             ||...|:.|:....::|:::.|
Human   261 -DGRWNDDVCQRPYRWVCETELD 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15358	NP_001303306.2	CLECT	141..245	CDD:153057	25/122 (20%)
ASGR1	NP_001662.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..30
		Endocytosis signal. /evidence=ECO:0000255	5..8
		Lectin_N	17..144	CDD:309178	14/60 (23%)
		CLECT_DC-SIGN_like	154..279	CDD:153060	29/139 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910