DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15358 and CLEC17A

DIOPT Version :9

Sequence 1:	NP_001303306.2	Gene:	CG15358 / 33366	FlyBaseID:	FBgn0031373	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001191047.1	Gene:	CLEC17A / 388512	HGNCID:	34520	Length:	378	Species:	Homo sapiens

Alignment Length:	183	Identity:	48/183 - (26%)
Similarity:	80/183 - (43%)	Gaps:	17/183 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 EARLARIETLQTAMNIRQKVLQEGFPKDIVARLDRLESQQAALLRILSKFD-RKIVAPK----FE 129
            |.|:...:.:....|:.......|...|| ||: |.::.| :|:.:....| |:|..|:    ||
Human   201 ELRMLSFQQMTWRTNMTGMAGLAGLKHDI-ARV-RADTNQ-SLVELWGLLDCRRITCPEGWLPFE 262

  Fly   130 LIGSRFFYIEDETRRNWTSAGSACRQMGTQLATIRSAEELAALRAKLNKERHYWLDITDLEKEGD 194
               .:.:|....| ::|..|...|::..:.|..|.|..|...:.......|.|||.:.|..:|||
Human   263 ---GKCYYFSPST-KSWDEARMFCQENYSHLVIINSFAEHNFVAKAHGSPRVYWLGLNDRAQEGD 323

  Fly   195 FR-ISASGKRPNFLKWRAGQPNNFSGNQHCVDL-LDGLMYDNKCESLSYFICQ 245
            :| :..|....:|  |...:|||.. ::.|..: ..|...|..|...:|:||:
Human   324 WRWLDGSPVTLSF--WEPEEPNNIH-DEDCATMNKGGTWNDLSCYKTTYWICE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15358	NP_001303306.2	CLECT	141..245	CDD:153057	29/105 (28%)
CLEC17A	NP_001191047.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..119
CLEC17A	NP_001191047.1	CLECT_DC-SIGN_like	254..374	CDD:153060	34/127 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9332
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910