DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15358 and CD209

DIOPT Version :9

Sequence 1:	NP_001303306.2	Gene:	CG15358 / 33366	FlyBaseID:	FBgn0031373	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_066978.1	Gene:	CD209 / 30835	HGNCID:	1641	Length:	404	Species:	Homo sapiens

Alignment Length:	118	Identity:	37/118 - (31%)
Similarity:	66/118 - (55%)	Gaps:	8/118 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   135 FF----YIEDETRRNWTSAGSACRQMGTQLATIRSAEELAALRAKLNKERHY-WLDITDLEKEGD 194
            ||    |....::|||..:.:||:::|.||..|:||||...|:.:.::...: |:.::||.:||.
Human   262 FFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGT 326

  Fly   195 FR-ISASGKRPNFLK-WRAGQPNNFSGNQHCVDLLDGLMYDNKCESLSYFICQ 245
            :: :..|...|:|.: |..|:|||. |.:.|.:.......|:||....::||:
Human   327 WQWVDGSPLLPSFKQYWNRGEPNNV-GEEDCAEFSGNGWNDDKCNLAKFWICK 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15358	NP_001303306.2	CLECT	141..245	CDD:153057	33/106 (31%)
CD209	NP_066978.1	Endocytosis signal	14..15
		Endocytosis signal. /evidence=ECO:0000255	16..18
		Endocytosis signal. /evidence=ECO:0000255	31..34
		transmembrane domain	36..59
		PilO	38..>184	CDD:294757
		neck domain	60..249
		CLECT_DC-SIGN_like	256..379	CDD:153060	37/118 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9332
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7163
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5578
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.990