DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15358 and FCER2

DIOPT Version :9

Sequence 1:	NP_001303306.2	Gene:	CG15358 / 33366	FlyBaseID:	FBgn0031373	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001207429.1	Gene:	FCER2 / 2208	HGNCID:	3612	Length:	321	Species:	Homo sapiens

Alignment Length:	267	Identity:	56/267 - (20%)
Similarity:	105/267 - (39%)	Gaps:	44/267 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SIW----LLLALFAWNAHAPSAAMPSVCLLQDAPQQCGEFCLTALSPMLDHIARHEGEWTSSVLQ 65
            ::|    .||.|:.|:.             ..:.:|..|.....:|.:..::..|.|:..:...|
Human    33 ALWAGLLTLLLLWHWDT-------------TQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQ 84

  Fly    66 A----------NATEARLARIETLQTAMNIR-----------QKVLQEGFPKDIVARLDRLESQQ 109
            :          .|.:.|| :.:.|:.:.|:.           |::.:.....|::.||....::.
Human    85 STQISQELEELRAEQQRL-KSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKL 148

  Fly   110 AALLRILSKFDRKIVAPKFELIGSRFFYIEDETRRNWTSAGSACRQMGTQLATIRSAEELAALRA 174
            ...|::.|.|.......|:.....:.:|....|:: |..|..||..|..||.:|.|.||...| .
Human   149 RMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQ-WVHARYACDDMEGQLVSIHSPEEQDFL-T 211

  Fly   175 KLNKERHYWLDITDLEKEGDFRISASGKRPNFLKWRAGQPNNFSGNQHCVDLL-DGLMYDNKCE- 237
            |.......|:.:.:|:.:|:| |...|...::..|..|:|.:.|..:.||.:. .|...|..|:
Human   212 KHASHTGSWIGLRNLDLKGEF-IWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDR 275

  Fly   238 SLSYFIC 244
            .|..::|
Human   276 KLGAWVC 282

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15358	NP_001303306.2	CLECT	141..245	CDD:153057	31/106 (29%)
FCER2	NP_001207429.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	66..85		2/18 (11%)
		Repetitive region	69..89		3/19 (16%)
		RILP-like	<77..153	CDD:304877	10/76 (13%)
		Repetitive region	90..110		4/20 (20%)
		Repetitive region	111..131		2/19 (11%)
		CLECT	163..282	CDD:214480	32/121 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..321
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22802
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X73
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010