DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15358 and Sftpd

DIOPT Version :9

Sequence 1:	NP_001303306.2	Gene:	CG15358 / 33366	FlyBaseID:	FBgn0031373	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_033186.1	Gene:	Sftpd / 20390	MGIID:	109515	Length:	374	Species:	Mus musculus

Alignment Length:	162	Identity:	47/162 - (29%)
Similarity:	79/162 - (48%)	Gaps:	12/162 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 QEGFPKDIVARLDRLESQQAALLRI---LSKFDRKIVAPKFELIGSRFFYIEDETRRNWTSAGSA 152
            :.|.| |..|...::|:.:..|.|:   .|.:.:..:.|....:|.:.|...| :.:.:..|...
Mouse   217 ESGLP-DSAALRQQMEALKGKLQRLEVAFSHYQKAALFPDGRSVGDKIFRTAD-SEKPFEDAQEM 279

  Fly   153 CRQMGTQLATIRSAEELAALRAKL---NKERHYWLDITDLEKEGDFRISASGKRPNFLKWRAGQP 214
            |:|.|.|||:.|||.|.||::..:   ||..  :|.:||:..||.|.. .:|:...:..|..|:|
Mouse   280 CKQAGGQLASPRSATENAAIQQLITAHNKAA--FLSMTDVGTEGKFTY-PTGEPLVYSNWAPGEP 341

  Fly   215 NNFSGNQHCVDLL-DGLMYDNKCESLSYFICQ 245
            ||..|.::||::. :|...|..|......||:
Mouse   342 NNNGGAENCVEIFTNGQWNDKACGEQRLVICE 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15358	NP_001303306.2	CLECT	141..245	CDD:153057	34/107 (32%)
Sftpd	NP_033186.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	38..222		2/5 (40%)
		Collagen	45..102	CDD:189968
		Collagen	129..>171	CDD:189968
		Surfac_D-trimer	223..267	CDD:286141	8/43 (19%)
		CLECT_collectin_like	261..374	CDD:153061	37/117 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	74	1.000	Inparanoid score	I5263
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960