DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG31663 and jef

DIOPT Version :9

Sequence 1:	NP_001259884.1	Gene:	CG31663 / 33363	FlyBaseID:	FBgn0051663	Length:	966	Species:	Drosophila melanogaster
Sequence 2:	NP_001246323.1	Gene:	jef / 36634	FlyBaseID:	FBgn0033958	Length:	762	Species:	Drosophila melanogaster

Alignment Length:	775	Identity:	148/775 - (19%)
Similarity:	242/775 - (31%)	Gaps:	297/775 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 FGEFCQRRGINPNLIMLKITLFVMYGATSSLLPYLTIHMQSIGLTVEEIAIIYLALPFTTFLSPP 88
            ||...:|     .||.:|...|..|.|..||.|.:.::.:.:|:...:..|:....||..|||.|
  Fly   105 FGASTER-----ELIPVKSFYFFFYAAFGSLFPLMGVYFKQMGMNPGQCGILVGMRPFVEFLSAP 164

  Fly    89 ITGFLVDKFGKYKPVVVMSLLLNAIFHHSLLFIPQQEIPGVVPSAFVLRHPDSGDIEVWWSPCPS 153
            ..|...|:..:.|.:::.||....:|              .:|.:|
  Fly   165 FWGSYADRCRQGKRLLLGSLACWVLF--------------TIPLSF------------------- 196

  Fly   154 RECPEEPELELAVHQCVDYCLMQEQVNPQLYTNTPAYDVRPAATTSTTQRSQLTATTARTTTMEP 218
                                                  :||.|.....:|:........|.|...
  Fly   197 --------------------------------------IRPEAINCIERRNATDFVLTYTRTKRD 223

  Fly   219 SSESSSSPAPTTSTTTSPASSLPAL-FATQTRSRYQEVLNMSSTMFPPMSQLKDALEEGVEPGQS 282
            .|...........|.|.||..  || .|....||::.            |.|...::.|:.|
  Fly   224 LSAMYEQEHLDMGTGTMPADE--ALEEAEAAHSRHKR------------SLLLPRIDAGISP--- 271

  Fly   283 SSAELSAMSMQGLNLTNSSQKKLLWSSWVH----SDNDDATYFMLQMHPDLADPTEQLGMEIEQD 343
                                        ||    |:.||      :.|.|...|.
  Fly   272 ----------------------------VHINFVSNYDD------KYHRDYVTPI---------- 292

  Fly   344 ANETVTDILQRFGHDYLVRGNINLTDMDDLDLRCGGLVRRTNMTNIASGAVECMMQRCTFTLNAP 408
                                             ...:|.||
  Fly   293 ---------------------------------FSSMVYRT------------------------ 300

  Fly   409 EICPPDYKETDEIIFWVYFLLRFLATTMLSAGVTIMDPIALTMIEKYGGDFGRERLFSSIGMAIF 473
                ||.::.    |::..|:..:.....:..:|:.|...:|::.:....:|.:|:|.|:|..|.
  Fly   301 ----PDIQKA----FFLLLLVILIGEFFSAPAITLADSAVITLLGEDADKYGHQRMFGSLGWGIS 357

  Fly   474 SPITGIMIDYSSR------GLGYTD--YSAAFYTYDVLLVISTMSVLMM-----PLGEKLPAD-- 523
            ..:.||.:|:|:.      |.|..:  |:..|..:.||:..:.:|...:     |:.|:|.|.
  Fly   358 MFLVGIALDHSTSFSNHPCGAGNKEKNYNICFSIFSVLMTCAIISASKITFKYDPIDEQLAAQQQ 422

  Fly   524 ---------------NVFRDLWNLLKM---------------------------PHV-------- 538
                           |......||..:                           ||:
  Fly   423 AQFVDPNKRAEEESMNQLAAQLNLPSLAVGSGSAASGACAGGVSSFLATGHQPQPHIGAESKVFA 487

  Fly   539 ------------------IAFICFLFV---LGNFWGFIESFLFLYLKELGAPNYLLGITITVGTV 582
                              :....||||   :|...|.|.:|||.:|::.|....|.|:...:..|
  Fly   488 QTAKELPEWMTVLTHFKDLKTASFLFVAWFMGFGIGLIFTFLFWHLQDYGGTPTLFGVASVINHV 552

  Fly   583 SSI-PFLYGAEKITRIFGHVNLIIIAFFSHAGRLVGYSFIETAWWCFPFEAMESLSCHLMWVAAA 646
            |.| .:.:....||:| |||.::.:....:..|.:..|::...|...|||.|:.::...:|.|:.
  Fly   553 SEIFAYFFSFRLITQI-GHVKVLCLGLIGNVLRFLYISYLTNPWMVLPFELMQGITHAAVWAASC 616

  Fly   647 TYCSILAPKSLLATLIGVLGMAHFSLGRGSGSFTGGLLIGQFGTRDAFRYMGL--LAVVG 704
            :|.:...||.|.|:..|||...|..||||.|:..||:.:..:||...||:.|:  |.|:|
  Fly   617 SYIAHNTPKHLRASAQGVLQGIHHGLGRGCGAIIGGMFVTYYGTTTTFRWYGIACLFVLG 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31663	NP_001259884.1	MFS_1_like	36..111	CDD:289593	22/74 (30%)
		MFS	<423..711	CDD:119392	87/371 (23%)
		MFS_1	<423..678	CDD:284993	76/341 (22%)
jef	NP_001246323.1	MFS	125..187	CDD:304372	17/61 (28%)
		MFS	508..>681	CDD:119392	56/170 (33%)
		MFS_1	511..>701	CDD:284993	56/167 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467103
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3762
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR16172
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840