Protein Alignment wry and dner

DIOPT Version :9

• Sequence 1: NP_995611.2
• Gene: wry / 33361
• FlyBaseID: FBgn0051665
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001116263.1
• Gene: dner / 779617
• XenbaseID: XB-GENE-478578
• Length: 678
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 168/607 - (27%)
• Similarity: 246/607 - (40%)
• Gaps: 152/607 - (25%)

  Fly   519 SAANPTKTASKPI---ARPRILSRLQEKINSLECEIPNVP--QDSHLWRGNETHELLLPIVTTEH 578
            ||...|.:.::||   ..|||             |:.:.|  |:...||.....:     |||
 Frog    85 SAEIVTPSHTEPIHSTTGPRI-------------EVAHSPAAQELPTWRPRVGQK-----VTT-- 129

  Fly   579 CKPDE-HCVPNVLTWRGEAEIQSGDILIVEINDAMLNPSHE-PNNTSSAV--HATQ----VYQVT 635
            .|.|| ..:|:|......:...||..|:          |.| ..|||..:  .||.    :::||
 Frog   130 LKWDEVQIIPDVACGNASSNTSSGGRLV----------SFEVAENTSVKISQDATAALILLWKVT 184

  Fly   636 RSGHEHCDVTEGVLLDITPLVVDGRKL--------VTLYDKDLTEGVNLLI-----VVSELWGAQ 687
            .||.:.|.            ::|||.:        :.|.|:.|..|.|..|     .||:  ...
 Frog   185 ASGFKQCS------------LIDGRSVTLLQALGGLVLPDEVLALGNNYFIGFVNDSVSK--SIV 235

  Fly   688 CVRLKVTTKTDNC---GENAD---CSGKGVCYSNSGMEEYECQCCSGFAGPHCEEIDACNPSPCT 746
            .:||.|..|..:|   |...|   |.|||.|.:.:..:.|.|.|.:|:.|.:|||.|||:..||.
 Frog   236 ALRLSVVVKITDCVPEGSLPDALQCHGKGDCLTKTTEDTYSCHCEAGYIGSYCEEFDACHLHPCL 300

  Fly   747 NNGICVDLSQGHEG--------------------------------------NSYQCLCPYGYAG 773
            ||..|.|:.|.|.|                                      :.:.|.||.|:.|
 Frog   301 NNASCTDIPQRHHGKNATCTCLPGYTGEHCEALVDHCSPQPCRNGATCTTSLSGFSCHCPEGFLG 365

  Fly   774 KNCQYESDPCNPAECMNGGSCVGNSTHFRCDCAPGFTGPLCQHSLNECESSPCVHGICVDQEDGF 838
            ..|:.:.|||..:.|:|.|||......:.|.|:||:|||.|...::.|..|||.||||......:
 Frog   366 SFCEEKVDPCAASPCLNNGSCTSAGISYSCRCSPGYTGPTCAQLVDFCALSPCAHGICRSIGTSY 430

  Fly   839 RCFCQPGFAGELCNFEYNECESNPCQNGGECIDHIGSYECRCTKGFSGNRCQIKVDFCANKPCPE 903
            :|.|.||:.|..|..|||||.|||||||..|.|.:..|:|.|...:.|..|::..|.|.|..|..
 Frog   431 KCLCIPGYHGLYCEEEYNECLSNPCQNGATCKDLVNGYQCVCPVEYEGLHCELYKDPCVNVSCQN 495

  Fly   904 GHRCIDHGNDFSCECPGGRNGPDCNQMPRTYFQQCNVNPCTHGGTCWSSGDSFYCACRPGYTGTM 968
            |..|...|.:.:|.|..|..|.:|    .....:|:.|||.|..||....:.:.|.|..|:.|..
 Frog   496 GGTCDSEGMNATCVCVPGFIGEEC----EIDVNECDSNPCHHASTCVDQVNGYTCHCPHGWVGAT 556

  Fly   969 CEDEF------VVETVVSSSEFIVDDANARNFNDKTFGSSVVLKSPIELHNAYFAAGVLAAAIFI 1027
            ||...      :.|::.:                            :..|:.|...|.|..|..:
 Frog   557 CEIHLQWKAGHMAESLTN----------------------------MPRHSLYIIIGALCVAFVL 593

  Fly  1028 VAVVVTICHCKVNQTYRKFSTR 1049
            :.:::.:..|::::...:.|:|
 Frog   594 MLIILIVGICRISRIEYQGSSR 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wry	NP_995611.2	EGF_CA	737..777	CDD:238011	17/77 (22%)
		EGF	783..812	CDD:278437	11/28 (39%)
		EGF_CA	819..851	CDD:238011	13/31 (42%)
		EGF_CA	856..890	CDD:238011	16/33 (48%)
		EGF_CA	893..927	CDD:238011	11/33 (33%)
		EGF_CA	<941..970	CDD:238011	10/28 (36%)
dner	NP_001116263.1	EGF_CA	46..78	CDD:238011
		EGF_CA	334..369	CDD:238011	5/34 (15%)
		EGF_CA	372..406	CDD:238011	15/33 (45%)
		EGF_CA	448..482	CDD:238011	16/33 (48%)
		EGF_CA	522..558	CDD:238011	11/35 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D199127at33208
OrthoFinder	1	1.000	-	-		FOG0008370
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6356
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010