Protein Alignment wry and notch2

DIOPT Version :9

• Sequence 1: NP_995611.2
• Gene: wry / 33361
• FlyBaseID: FBgn0051665
• Length: 1157
• Species: Drosophila melanogaster
• Sequence 2: NP_001108566.2
• Gene: notch2 / 58065
• ZFINID: ZDB-GENE-000329-4
• Length: 2475
• Species: Danio rerio
• Alignment Length: 513
• Identity: 148/513 - (28%)
• Similarity: 209/513 - (40%)
• Gaps: 108/513 - (21%)

  Fly   482 PPK--------SVDKSTASPSSTTSTSTSTTTT----------MATLLATARTRPSAANPTKTAS 528
            ||:        .||:....|::..:..|.:.|.          .:.|..:......||.|....|
Zfish   289 PPEWTGQFCTDDVDECRLQPNACQNGGTCSNTRNGYNCVCVNGWSGLDCSENIDDCAAEPCTAGS 353

  Fly   529 KPIARPRILSRLQEKINSLECEIPNVPQDSHLWRGNETHELLLPI---VTTEHCKPDEHCVPNVL 590
            ..|          :::.|..|..|  |..:         .||..|   ..:..||...||..|.:
Zfish   354 TCI----------DRVASFVCSCP--PGKT---------GLLCHIDDACISNPCKMGAHCDTNPV 397

  Fly   591 TWRGEAEIQS---GDILIVEINDAMLNPSHEPNNTSSAVHATQVYQVTRSGHEHCDVTEGVLLDI 652
            ..:......|   |.....:|::.::.|:...:..|                  |..|||
Zfish   398 NGKFSCNCPSGYKGSTCAEDIDECVIGPNPCEHGGS------------------CKNTEG----- 439

  Fly   653 TPLVVDGRKLVTLYDKDLTEGVNLLIVVSELWGAQCVRLKVTTKTDNCGENADCSGKGVCYSNSG 717
                        .:..:...|..         |.:|.:     ..:.||.| .|.....|....|
Zfish   440 ------------SFTCNCAPGYT---------GPRCEQ-----DINECGSN-PCQNDATCLDQIG 477

  Fly   718 MEEYECQCCSGFAGPHCE-EIDACNPSPCTNNGICVDLSQGHEGNSYQCLCPYGYAGKNCQYESD 781
              :|.|.|..||.|.||| :|:.|..|||.|||.|:|     :.:.:.|.||.|:.|:.||.:.|
Zfish   478 --DYTCICMPGFDGTHCENDINECLSSPCLNNGRCLD-----QVSRFVCECPQGFTGETCQVDID 535

  Fly   782 PCNPAECMNGGSCVGNSTHFRCDCAPGFTGPLCQHSLNECESSPCVHGICVDQEDGFRCFCQPGF 846
            .|....|.||..|:.....:.|:||.|||||||..::|:||..||.||.|:|....|.|.|.||:
Zfish   536 ECASTPCHNGAKCLDRPNGYECECAEGFTGPLCMENINDCEPQPCHHGKCIDGIATFHCDCLPGY 600

  Fly   847 AGELCNFEYNECESNPCQNGGECIDHIGSYECRCTKGFSGNRCQIKVDFCANKPCPEGHRCIDHG 911
            .|.:|:.:..||:|:||||||.|:|.:..|:|.|..|.:|..|||..|.||:.||..| .|.|..
Zfish   601 MGPICSEQIRECQSDPCQNGGRCVDMVNRYQCNCQPGTAGENCQINYDDCASNPCQHG-TCEDGI 664

  Fly   912 NDFSCECPGGRNGPDCNQMPRTYFQQCNVNPCTHGGTCWSSGDSFYCACRPGYTGTMC 969
            |::.|.|..|..|..|    .....:|:.|||..||||....:.|.|.|..|..|.:|
Zfish   665 NEYKCVCEPGYTGERC----ADEINECSSNPCQSGGTCEDKVNGFKCKCPVGTYGPLC 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wry	NP_995611.2	EGF_CA	737..777	CDD:238011	15/39 (38%)
		EGF	783..812	CDD:278437	11/28 (39%)
		EGF_CA	819..851	CDD:238011	15/31 (48%)
		EGF_CA	856..890	CDD:238011	16/33 (48%)
		EGF_CA	893..927	CDD:238011	13/33 (39%)
		EGF_CA	<941..970	CDD:238011	13/29 (45%)
notch2	NP_001108566.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	50	1.000	Domainoid score	I11644
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D7525at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010