DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wry and dsl-4

DIOPT Version :9

Sequence 1:	NP_995611.2	Gene:	wry / 33361	FlyBaseID:	FBgn0051665	Length:	1157	Species:	Drosophila melanogaster
Sequence 2:	NP_001359594.1	Gene:	dsl-4 / 184563	WormBaseID:	WBGene00001106	Length:	368	Species:	Caenorhabditis elegans

Alignment Length:	277	Identity:	76/277 - (27%)
Similarity:	112/277 - (40%)	Gaps:	52/277 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   663 VTLYDKDLTEGVNLLIVVSELWGAQCVRLKVTTKTDN---------CGENADCSGKGVCYSNSGM 718
            :::||.:..|.:.|..:|..| ........|.||.|:         |.||.......:...:...
Worm    81 ISIYDINDEEPLGLEQIVVPL-TRHFSNFTVHTKNDSFLHFAVRNVCDENWRTHSCSIFCKDRSD 144

  Fly   719 EEYEC------QCCSGFAGPHCEEIDACNPSPCTNNGICVDLSQGHEGNSYQCLCPYGYAGKNCQ 777
            .:::|      :|..|::||:|:::|.  |..|.|:|.|....        :|:|..|:.|..|:
Worm   145 SKFKCDDDDGYKCAPGYSGPNCDKVDC--PFNCHNHGSCEVPG--------KCMCSQGFFGTYCE 199

  Fly   778 YESDPCNPA-ECMNGGSCVGN-STH-FRCDCAPGFTG------PLCQHSLNECESSPCVHGICVD 833
            |    |.|: .|.:|...|.. ..| :.|.|..|:.|      .:|.:      :.||.||.||.
Worm   200 Y----CKPSTTCKHGAVLVNELGCHPYTCRCFEGYAGDNGDKDDVCYY------AKPCRHGNCVS 254

  Fly   834 Q---EDGFRCFCQPGFAGELCN---FEYNECESNPCQNGGECIDHIGSYECRCTKGFSGNRCQIK 892
            .   ..||.|.|...|.|..|.   ..::..:...|||.|.|....|...|||..||:|..|:.|
Worm   255 NVTVSGGFECICPKAFGGRRCEKRIARWDCSDEGYCQNKGVCSFVDGISRCRCAVGFTGKHCERK 319

  Fly   893 -VDFCANKPCPEGHRCI 908
             ...|..|.|.||..||
Worm   320 TAKTCLKKKCREGFICI 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wry	NP_995611.2	EGF_CA	737..777	CDD:238011	10/39 (26%)
		EGF	783..812	CDD:278437	10/37 (27%)
		EGF_CA	819..851	CDD:238011	12/34 (35%)
		EGF_CA	856..890	CDD:238011	12/33 (36%)
		EGF_CA	893..927	CDD:238011	7/16 (44%)
		EGF_CA	<941..970	CDD:238011
dsl-4	NP_001359594.1	DSL	110..166	CDD:366627	12/55 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24044
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010